Simultaneous Quantitative Analysis of Six Isothiazolinones in Water-Based Adhesive Used for Food Contact Materials by High-Performance Liquid Chromatography–Tandem Mass Spectrometry (HPLC–MS/MS) [PDF]
Molecules, 2019 In this study, a target analytical approach using high-performance liquid chromatography−tandem mass spectrometry (HPLC−MS/MS) was developed to simultaneously determine six isothiazolinones containing 2-Methylisothiazol-3(2H)-one (MI), 5 ...
Ying Zeng
exaly +4 more sources
Procoagulant Effects of Isothiazolinone Biocides, Benzisothiazolinone and Octylisothiazolinone in Platelets [PDF]
ToxicsIsothiazolinones are commonly used biocides that are extensively used in industrial areas and household products. The extensive usage of isothiazolinones raises concerns regarding their adverse human health effects.
Ju Hee Choi, Keunyoung Kim
doaj +2 more sources
Disposition of Aerosols of Isothiazolinone-Biocides: BIT, MIT and OIT [PDF]
Toxics, 2022 Biocides are widely used in everyday life, and accordingly, human exposure to them is inevitable. Especially, the inhalational exposure of humans to biocides and resultant respiratory toxicity are gaining public interest due to the recent catastrophe ...
Seungmi Lee +5 more
doaj +2 more sources
Isothiazolinones as Novel Candidate Insecticides for the Control of Hemipteran Insects [PDF]
Antibiotics, 2021 Hemipteran insects, such as whiteflies, aphids and planthoppers, resemble one of the most important pest groups threating food security. While many insecticides have been used to control these pests, many issues such as insecticide resistance have been ...
Wenze He +3 more
doaj +2 more sources
Allergic contact dermatitis to isothiazolinones in a rubber factory: A case report [PDF]
Clinical Case Reports, 2022 Isothiazolinones, used as preservative, are known to be skin sensitizers. Although cosmetics represent their main source, occupational exposure may be a significant origin of eczema.
Anouare Hrairi +9 more
doaj +2 more sources
Nanostructured Carbon and Gold Screen-Printed Electrodes for Sensitive Detection of Benzisothiazolinone in Environmental Water Samples [PDF]
SensorsBenzisothiazolinone (BIT) is a commonly used biocide in water-based products, which can enter the environment from household and personal care products, as well as from leaching off building facades and roofs due to rainfall, eventually reaching rivers ...
Jelena Vujančević +3 more
doaj +2 more sources
Development of a Generic Analysis Method for Isothiazolinones in Consumer Products Prompted by Increased Sensitisation to Benzisothiazolinone. [PDF]
Contact DermatitisAn analysis method using simple instrumentation was developed to investigate isothiazolinones in cosmetic and household products in patch test investigations. Analysis showed that concentrations of benzisothiazolinone can be several orders of magnitude higher than those of chloromethylisothiazolinone/methylisothiazolinone in products to which skin ...
Farbrot A +8 more
europepmc +2 more sources
Contact Sensitisation Trends in Slovenian Children and Adolescents: A Retrospective Single-Centre Study. [PDF]
Contact DermatitisNickel sensitisation in children decreased significantly over time, while dyes and isothiazolinones are emerging allergens. These findings underscore shifting exposure patterns and the need for continuous surveillance to guide effective patch testing and prevention strategies.
Zorko MS, Lunder T, Peric T.
europepmc +2 more sources
Prevalence of Contact Allergy to Isothiazolinones in Dermatitis Patients From 2000 to 2025: A Systematic Review and Meta-Analysis. [PDF]
Contact DermatitisABSTRACT Isothiazolinones are employed in the preservation of cosmetic, consumer and industrial products, with the objective of preventing deterioration and spoilage. However, the utilization of isothiazolinones is associated with an elevated risk of developing contact allergy (CA).
Isufi D +6 more
europepmc +2 more sources
Effect of Cosmetics Use on the In Vitro Skin Absorption of a Biocide, 1,2-Benzisothiazolin-3-one [PDF]
Toxics, 2022 1,2-Benzisothiazolin-3-one (BIT) is a commonly used organic biocide containing an isothiazolone ring. However, it may have adverse effects on human health and its risk needs to be properly evaluated. Dermal exposure is the main route of BIT exposure, and
Yoonjung Huh +3 more
doaj +2 more sources