Results 11 to 20 of about 648 (166)

Allergy to isothiazolinones in recent years [PDF]

Medycyna Pracy, 2020
Background Isothiazolinones are preservatives which are present in cosmetics, household chemicals and many other industrial products. Initially, a mixture of methylchloroisothiazolinone and methylisothiazolinone (MCI/MI – Kathon CG) was used, and then ...
Ewa Nowakowska-Świrta, Marta Kieć-Świerczyńska   +1 more
doaj   +4 more sources

Isothiazolinones in Disposable Rubber Gloves-Results of Chemical Analysis. [PDF]

Contact Dermatitis
Chemical analysis revealed benzisothiazolinone (BIT) in 30/54 disposable rubber gloves (27 nitrile rubber gloves, 2 neoprene rubber gloves and 1 natural rubber glove) in concentrations of 0.3–73.7 ppm. Methylisothiazolinone (MI) was found in six nitrile rubber gloves in small concentrations.
Suuronen K, Ylinen K, Suomela S, Pesonen M.   +3 more
europepmc   +3 more sources

Isothiazolinones Common in Children's Toy Slime

Dermatitis®, 2021
: Background Contact dermatitis to homemade slime has been frequently reported, with isothiazolinones as a likely sensitizer. Little is known on the presence of these preservatives in commercial, store-bought slime products.
Aerts, Olivier, Kathryn A. Zug, Keegan O'Hern, Liang, Shu T., Carsten R. Hamann, O'Hern, Keegan, Hamann, Carsten R., Ella Dendooven, Shu T. Liang, Olivier Aerts, Dendooven, Ella, Zug, Kathryn A.   +11 more
core   +4 more sources

Isothiazolinones Quantification in Shampoo Matrices: A Matter of Method Optimization or Stability Driven by Interactions?

Cosmetics, 2020
Methylisothiazolinone (MI) is one of the most used preservatives in shampoos and also one of the most effective. A preservative mixture known as Kathon™ CG is commercially available.
Mariana Tomás, Ana Sofia Agonia, Lígia Borges, Ana Palmeira de Oliveira, Rita Palmeira de Oliveira   +4 more
doaj   +2 more sources

Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles [PDF]

Molecules, 2020
The importance of isothiazole and of compounds containing the isothiazole nucleus has been growing over the last few years. Isothiazolinones are used in cosmetic and as chemical additives for occupational and industrial usage due to their bacteriostatic ...
Vânia Silva, Cátia Silva, Pedro Soares, E. Manuela Garrido, Fernanda Borges, Jorge Garrido   +5 more
doaj   +4 more sources

Methylchloroisothiazolinone and Methylisothiazolinone 10 Years After Regulation: A Case Story of Liquid Soaps and Shampoos. [PDF]

Contact Dermatitis
MCI/MI and MI contact allergy remain persistent. In this analysis of the Danish market, 257 products containing MCI/MI or MI were identified, and 30 products were analysed. Two exceeded regulatory limits, while most complied, suggesting current limits may require further investigation. Created in BioRender. Pedersen, M. K.
Pedersen MK, Schwensen JFB, Alfonso JH, Kirkeby CS, Müller S, Mollerup S, Selvestrel G, Rudén C, Wilks MF, Johansen JD.   +9 more
europepmc   +2 more sources

Octylisothiazolinone-A New Sensitizer in Over-Ear Headphones. [PDF]

Contact Dermatitis
Two cases of allergic contact dermatitis from over‐ear headphones are presented. OIT was confirmed by chemical analysis in one case and implicated by patch testing in the other, underscoring its relevance as a sensitiser in consumer products. ABSTRACT Background Allergic contact dermatitis (ACD) caused by isothiazolinones is a growing concern ...
Berisha B, Lejding T, Bergendorff O, Hauksson I.   +3 more
europepmc   +2 more sources

Clinical Factors Associated With Current Relevance in Allergic Contact Dermatitis: Development of Predictive Models Based on Data From the Spanish Contact Dermatitis Register (REIDAC). [PDF]

Contact Dermatitis
This study has shown a moderate performance of the regression model to predict current relevance (AUC = 0.679), although modelling performance has been better for specific allergens (e.g., nickel with an AUC = 0.770). Furthermore, it has identified key predictors, including female gender, specific involved sites (hands, neck, head, legs, feet), and ...
Pesqué D, Ortiz de Frutos FJ, Navarro-Triviño F, Sanz-Sánchez T, Zaragoza-Ninet V, Córdoba-Guijarro S, Miquel-Miquel J, Silvestre-Salvador JF, González-Pérez R, Ruiz-González I, Mercader-García P, Serra-Baldrich E, Carrascosa-Carrillo JM, Tous-Romero F, Rodríguez-Serna M, Gatica-Ortega ME, Paredes-Suárez C, Pastor-Nieto MA, Chicharro P, Andreu M, Sánchez-Gilo A, Pereyra-Rodríguez JJ, Melé-Ninot G, Sánchez-Pedreño Guillén P, Gómez de la Fuente E, Elosua-González M, Gallardo F, Pujol RM, García-Doval I, Borrego L, Descalzo MÁ, Giménez-Arnau AM.   +31 more
europepmc   +2 more sources

Occurrence and concentrations of isothiazolinones in detergents and cosmetics in Switzerland.

Contact Dermatitis, 2017
BACKGROUND In recent years, the frequency of contact allergy to isothiazolinones has increased alarmingly in Europe, but only limited data are available on concentrations of isothiazolinones in consumer products.
Sottas V, Hauri U, Hungerbühler K, Garcia-Hidalgo E, Bogdal C, von Goetz N   +5 more
core   +4 more sources

The skin allergy risk assessment-integrated chemical environment (SARA-ICE) defined approach to derive points of departure for skin sensitization [PDF]

Current Research in Toxicology
Mechanistically based non-animal methods for assessing skin sensitization hazard have been developed, but are not considered sufficient, individually, to conclusively define the skin sensitization potential or potency of a chemical.
Emily N. Reinke, Joe Reynolds, Nicola Gilmour, Georgia Reynolds, Judy Strickland, Dori Germolec, David G. Allen, Gavin Maxwell, Nicole C. Kleinstreuer   +8 more
doaj   +2 more sources