Results 211 to 220 of about 17,936 (269)

Ribonucleic acid biosynthesis in methylcholanthrene-treated rats

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966
Abstract The incorporation of [ 14 C]orotic acid into whole liver RNA and nuclear RNA was examined at various times after a single administration of 3-methylcholanthrene. No significant change in specific activity was observed. Zonal ultracentrifugation patterns of nuclear RNA were also unaffected by pretreatment of the rats with 3 ...
E, Bresnick, R, Brand, J A, Knight
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Fluorescence of Methylcholanthrene

Nature, 1942
THE letter on “Fluorescent Lipoidal Spectra of Human Tissue” in NATURE of February 14, p. 193, requires comment upon several points.
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Epidermal Innervation in Methylcholanthrene-painted Mouse Skin

Nature, 1965
IN order to investigate the innervation of experimental tumours, we painted the right ear and flank of BALB mice with a saturated solution of 20-methylcholanthrene (MCA) in benzene, and painted the left side with benzene alone. We have found that MCA evokes a prompt growth response by the regional cutaneous nerves.
M J, FITZGERALD, S M, LAVELLE
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Methylcholanthrene-induced Lymphosarcomas in Xenopus laevis

Nature, 1962
THE number of spontaneous neoplasms found in Amphibia1 and the success of Leono2,3 in chemically inducing tumours in newts uphold the view4 that Amphibia, like other vertebrates, are susceptible to tho occurrence of neoplastic growth.
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A Test for Mutagenicity of Methylcholanthrene

Nature, 1948
RECENT results by Strong1,2 and by Carr3 on mice, and by Demerec4 on Drosophila, have focused interest on a possible connexion between mutagenicity and carcinogenicity, which in the past has often been claimed on theoretical grounds. While Auerbach5 failed to produce mutations by injection of 1 : 2 : 5 : 6 dibenzanthracene into Drosophila, Demerec ...
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Uptake of methylcholanthrene in the rat pancreas

The American Journal of Digestive Diseases, 1974
Epidemiologic studies show an increase in the incidence of pancreatic carcinoma and suggest that this increase may result, at least in part, from increased exposure to chemical carcinogens. Little information is available concerning the uptake of such agents or their effects on the pancreas.
O, Black, P D, Webster
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Serum increases CYP1A1 induction by 3-methylcholanthrene

Biochemical and Biophysical Research Communications, 2002
CYP1A1 is largely involved in carcinogenesis through the bioactivation of numerous procarcinogens. Exposure to environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs) leads to induction of CYP1A1 via AhR pathway. We have previously demonstrated that fetal bovine serum (FBS) induces CYP1A1 gene transcription.
Quoc-Binh, N'Guyen, Frederique, Fallone, Eric, Seree, Frederic, Fina, Pierre-Henri, Villard, Nolwen, Guigal, Michel, De Meo, Bruno, Lacarelle, Pierre-Marie, Martin, Yves, Barra   +9 more
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Microsomal and nuclear metabolism of 3-methylcholanthrene

Biochemical Pharmacology, 1979
Abstract Hepatic nuclei and microsomes prepared from rats pretreated with 3-methyleholanthrene, or hepatic nuclei prepared from untreated rats, were incubated with generally 3H-labeled 3-methylcholanthrene in the presence of an NADPH-generating system.
B, Tierney, E, Bresnick, P, Sims, P L, Grover   +3 more
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Metabolism of Radioactive Methylcholanthrene in the Rat

Nature, 1963
IT has long been known that the administration of methylcholanthrene by the alimentary tract can produce mammary tumours in certain strains of mice and rats. Prohaska, Brunschwig and Wilson1 first reported four mammary tumours in 15 mice fed 1.2 mg methylcholanthrene three times weekly for up to six weeks.
A L, FOODALL, M H, McINTYRE, J S, KENNEDY   +2 more
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Progestin secretion in 3‐methylcholanthrene‐treated rats

International Journal of Cancer, 1972
AbstractThe mechanism of deciduomata maintenance by 3‐methylcholanthrene (MCA) was investigated in normally cycling Sprague‐Dawley rats. Animals received daily injections of ovine prolactin (LTH) from days 1‐4 following estrus (pre‐trauma period).
R C, Moon, S, Young
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