Alpha-methyldopa in schizophrenia
Reports a case of a 42-yr-old male schizophrenic in whom, after an overdose of alpha-methyldopa, there was a dramatic and apparently complete resolution of psychotic symptomatology, followed after a few weeks by a sudden return of psychosis.
Gaind, R. +2 more
core +6 more sources
Spectrophotometric Determination of Methyldopa in Pure and Pharmaceutical Preparations by the Oxidative Coupling Reaction with 1, 5-Diaminonaphthalene in the Presence of Ammonium Ceric (IV) Nitrate [PDF]
Oxidative coupling reactions are one of the significant methods used in the estimation of certain drugs in pharmaceutical formulations. This study describes the development of a fast and sensitive spectroscopic method considering the determination of ...
Noor Mansoor Ghaib Allah +2 more
doaj +1 more source
Novel Strongly Basic Molecularly Imprinted Solid-Phase Extraction Sorbent for Simultaneous Determination of Catecholamines and Their Metabolites in Urine. [PDF]
ABSTRACT Catecholamines are important hormones and neuromediators in the human body. Simultaneous determination of both catecholamines and catecholamine metabolites in bodily fluids can help accurately diagnose dangerous health conditions like adrenal tumors.
Šilaks A +4 more
europepmc +2 more sources
The aim of the study was to investigate the effect of baicalein or Scutellaria baicalensis root extract interaction with methyldopa in pregnant spontaneously hypertensive rats (SHR) at the pharmacodynamic, molecular, and biochemical levels.
Michał Szulc +17 more
doaj +1 more source
The effect of antihypertensive treatment on longitudinal changes in PLGF and sFlt-1 in women with new onset hypertension in pregnancy. [PDF]
In pregnant women with new‐onset hypertension starting antihypertensives, some achieve tight BP control within a week (Group 1‐blue line), while others respond slower (Group 2‐red line). Group 1 showed higher Log10PLGF levels, but Log10sFlt‐1 did not differ between groups. Over time, Log10PLGF declined in both groups, while Log10sFlt‐1 remained stable.
Tyrell E +4 more
europepmc +2 more sources
The aim of the study was to investigate combined effects of flavonoids (apigenin, baicalein, chrysin, quercetin, and scutellarin) and methyldopa on the expression of selected proinflammatory and vascular factors in vitro for prediction of their action in
Anna Bogacz +10 more
doaj +1 more source
Resolution of Preeclampsia After Single Selective Termination in Twins: A Case Series and Literature Review. [PDF]
ABSTRACT Preeclampsia significantly contributes to maternal and perinatal morbidity and mortality, with twin pregnancies increasing this risk. Severe preeclampsia often requires pregnancy termination to protect maternal health. We report two cases of IVF‐conceived twin pregnancies complicated by early preeclampsia. The first case involved a 34 year‐old
Golshahi F +8 more
europepmc +2 more sources
Effect of Antihypertensive Drugs on Placental Villi of Preeclamptic Patients: A Histopathological Study [PDF]
Background & Aims: The placenta has been described as the most accurate record of the infant’s prenatal experience. The present study was a quantitative study and it was carried out to see the effect of pre-eclampsia on histopathology of placenta and ...
Hamid Ansari +3 more
doaj
Effect of antihypertensive therapy with alpha methyldopa on levels of angiogenic factors in pregnancies with hypertensive disorders. [PDF]
Antihypertensive drugs are believed to lower blood pressure in pre-eclampsia by direct or central vasodilatory mechanisms. However, they could also act by decreasing production of anti-angiogenic proteins involved in the pathophysiology of hypertension ...
Muttukrishna Shanthi +11 more
core +2 more sources
Background: Pre-eclampsia is culmination of a multi-step process that related in part to elevated oxidative stress and associated with hyperurecimia. Patients and methods: Thirty normotensive and hundred pre-eclamptic pregnant women attending to Al-Basra
Ghassan S. Ahmed, May S. Al-Sabbagh
doaj +1 more source

