Results 31 to 40 of about 8,909 (191)

Analysis of Methyldopa Therapy on sFlt-1 Antiangiogenic Levels in Patients with Severe Preeclampsia

Folia Medica Indonesiana, 2018
Methyldopa is the first-line drugs to treat hypertension in pregnancy. It can decrease blood pressure in preeclampsia by affecting a2-adrenoreceptors in central nervous system. However, it could also act by decreasing  production of sFlt-1 antiangiogenic
Teri Wina Herwati, Yulistiani Yulistiani, Eddy Zarkaty M   +2 more
doaj   +1 more source

Spectrophotometric determination of methyldopa in pharmaceutical formulations [PDF]

, 2005
A new, simple, precise, rapid and low-cost spectrophotometric method for methyldopa determination in pharmaceutical preparations is described. This method is based on the complexation reaction of methyldopa with molybdate.
Pezza, Leonardo [UNESP], Ribeiro, P. R S, Pezza, Leonardo, Pezza, Helena Redigolo [UNESP], Ribeiro, P. R S [UNESP], Pezza, Helena Redigolo   +5 more
core   +1 more source

EFFECTS OF METHYLDOPA ON VEGF LEVELS AS PROANGIOGENIC FACTOR IN SEVERE PRE-ECLAMPSIA AT HAJI HOSPITAL, SURABAYA

Folia Medica Indonesiana, 2017
Methyldopa is the main antihypertensive drug widely used in pregnant women with hypertensive disorder. It lowers blood pressure in pre-eclampsia by affecting a2-adrenoreceptors in central nervous system.
Dina Ratna Juwita, Yulistiani Yulistiani, Eddy Zarkaty M   +2 more
doaj   +1 more source

Comparison of Lasix and Methyldopa in Controlling Hypertension in preeclampsia patients: A Double-Blind Randomized Clinical Trial

Men's Health Journal, 2020
Introduction: Preeclampsia is a specific gestational syndrome that reduces organ perfusion due to vascular spasm and endothelial activation. Despite the use of magnesium sulfate, the patient's blood pressure sometimes remains uncontrolled, and therefore,
Setareh Siamansoori, Elahe Afshari, Maryam Palizdar, Mohammad Ali Hosseini   +3 more
doaj   +1 more source

EFFECT OF PREGNANCY ON THE HYPOTENSIVE ACTION OF ANGIOTENSIN – CONVERTING ENZYME INHIBITORS IN FEMALE RATS

Zagazig Journal of Pharmaceutical Sciences, 1997
The effect of angiotensin-converting enzyme (ACE) inhibitors versus alpha methyldopa on the arterial blood pressure of pregnant adult female rats were studied.
Salah Ghareib
doaj   +1 more source

Phenotypic Exploration in Patients with Heterozygous Variant in AFG3L2 Gene: A Case‐Series and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Variants in AFG3‐Like Matrix AAA Peptidase, Subunit 2 (AFG3L2) gene are associated with diverse clinical phenotypes. Here, we describe phenotypic findings of two unrelated children with de novo heterozygous variant and one family with inherited heterozygous variant in AFG3L2 gene.
Sangeetha Yoganathan, Laura Tochen, Jacky Ganguly, Sayoni Roy Chowdhury, Haya S AlFaris, Vivek Pai, Andrea LeBlanc‐Millar, Sara Breitbart, Hrishikesh Kumar, Manohar Shroff, Arun Reginald, Grace Yoon, Alfonso Fasano, George M Ibrahim, Carolina Gorodetsky   +14 more
wiley   +1 more source

Maternal and neonatal outcomes of antihypertensive treatment in pregnancy: A retrospective cohort study.

PLoS ONE, 2022
ObjectiveTo compare maternal and infant outcomes with different antihypertensive medications in pregnancy.DesignRetrospective cohort study.SettingKaiser Permanente, a large healthcare system in the United States.PopulationWomen aged 15-49 years with a ...
Sascha Dublin, Abisola Idu, Lyndsay A Avalos, T Craig Cheetham, Thomas R Easterling, Lu Chen, Victoria L Holt, Nerissa Nance, Zoe Bider-Canfield, Romain S Neugebauer, Kristi Reynolds, Sylvia E Badon, Susan M Shortreed   +12 more
doaj   +1 more source

Safety of Venom Immunotherapy in Pregnancy: A Multicentre Study

Allergy, EarlyView.
Venom immunotherapy (VIT) during pregnancy, when maintenance dose is well tolerated, can be continued. No increased risk of adverse effects to VIT or safety concerns for the pregnancy or the newborns were observed. No decreased efficacy of VIT, in case of re‐stings, was reported.
Matteo Martini, Giovanna Sfriso, Valerio Pravettoni, Marina Mauro, Donatella Preziosi, Francesca Vettorato, Giuseppe Lucchini, Mauro Pagani, Iuliana Badiu, Maria Pia Dolcher, Francesco Gaeta, Pietro Galati, Elisa Meucci, Elide Pastorello, Vincenzo Patella, Stefano Pucci, Chiara Roncallo, Eleonora Savi, Livio Simioni, Maria Beatrice Bilò, Patrizia Bonadonna   +20 more
wiley   +1 more source

Synthesis, Characterization and Biological Efficacies from Some New Dinuclear Metal Complexes for Base 3-(3,4-Dihydroxy-phenyl)-2-[(2-hydroxy-3-methylperoxy-benzylidene)-amino]-2-methyl Propionic Acid

Indonesian Journal of Chemistry, 2020
The reaction of methyldopa with o-vanillin in refluxing ethanol afforded Schiff base and characterized through physical analysis with a number of spectra also the study of biological activity. The geometry of the Schiff base was identified through using (
Shatha Mohammed Hassan Obaid, Jasim Shihab Sultan, Abbas Ali Salih Al-Hamdani   +2 more
doaj   +1 more source

Hypertensive Disorders in Pregnancy: A Comparative Analysis of Clinical Guidelines Across Six High‐Income Countries

Birth, EarlyView.
ABSTRACT Background Women in the United States (U.S.) experience higher maternal morbidity and mortality than other high‐income countries, with hypertensive disorders of pregnancy (HDP) among the most common, preventable contributors. Despite evidence supporting pharmacologic intervention, American College of Obstetricians and Gynecologists (ACOG ...
Kortney Floyd James, Alyssa A. Portes, Kandice A. Kapinos, Lucinda Canty, Gabriela Alvarado, Karen A. Scott   +5 more
wiley   +1 more source