Results 51 to 60 of about 13,801 (241)

The effect of α-methyldopa on excretion of noradrenaline metabolites

, 1967
The effect of α-methyldopa on the rate of release of noradrenaline metabolites in patients with essential hypertension has been examined. The excretion of normetadrenaline increases during the first few hr after a dose of α-methyldopa while α ...
R ROBINSON, A W STOTT
core   +1 more source

The effect of antihypertensive treatment on longitudinal changes in PLGF and sFlt‐1 in women with new onset hypertension in pregnancy

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1515-1522, August 2026.
In pregnant women with new‐onset hypertension starting antihypertensives, some achieve tight BP control within a week (Group 1‐blue line), while others respond slower (Group 2‐red line). Group 1 showed higher Log10PLGF levels, but Log10sFlt‐1 did not differ between groups. Over time, Log10PLGF declined in both groups, while Log10sFlt‐1 remained stable.
Edward Tyrell, Katherine G. Y. Lau, Martyna Bednorz, Kypros H. Nicolaides, Nikos A. Kametas   +4 more
wiley   +1 more source

Interaction Between NOS3 and HMOX1 on Antihypertensive Drug Responsiveness in Preeclampsia [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2020
Objective We examined the interaction of polymorphisms in the genes heme oxygenase- 1 (HMOX1) and nitric oxide synthase (NOS3) in patients with preeclampsia (PE) as well as the responsiveness to methyldopa and to total antihypertensive therapy. Methods
Valeria Cristina Sandrim, Marcelo Rizzatti Luizon, Eliane Pilan, Mayara Caldeira-Dias, Fernanda Borchers Coeli-Lacchini, Georgia Kors, Iuly Berndt, Riccardo Lacchini, Ricardo Carvalho Cavalli   +8 more
doaj   +1 more source

Simultaneous determination of serum concentration of levodopa, dopamine, 3-O-methyldopa and alfa-methyldopa by HPLC

, 2008
Levodopa is the medication of choice for Parkinson's disease. The biological complexity of levodopa and of its main derivatives makes their determination important in the clinical field.
PORCELLI B., CIARI I., PAGANI R., BERTOCCI E., MUZZI C., TERZUOLI L., GUERRANTI R.   +6 more
core   +1 more source

DETERMINAÇÃO ESPECTROFOTOMÉTRICA DE METILDOPA EM ENSAIO DE DISSOLUÇÃO DE COMPRIMIDOS UTILIZANDO EXTRATO DE RABANETE COMO FONTE DE PEROXIDASE

Química Nova, 2015
An enzymatic spectrophotometric method for the determination of methyldopa in a dissolution test of tablets was developed using peroxidase from radish (Raphanus sativus).
Natielle Gianine Bueno, Airton Vicente Pereira   +1 more
doaj   +1 more source

A METHOD FOR QUANTIFICATION OF PLASMA CONCENTRATIONS OF METHYLDOPA

, 2017
We developed a rapid and sensitive method for quantifying plasma concentrations of methyldopa using HPLC-MS/MS. The range of concentration measurements was 0,02-3,00 цд/ml.
A. M. Shitova, Y. A. Dzhurko, I. I. Yaichkov, V. Kubes, A. L. Khokhlov, L. N. Shitov   +5 more
core   +1 more source

Alpha-Methyldopa-Induced Autoimmune Hemolytic Anemia in the Third Trimester of Pregnancy

Case Reports in Obstetrics and Gynecology, 2013
Alpha-methyldopa has been demonstrated to be safe for use during pregnancy and is now used to treat gestational hypertension. In pregnancy, alpha-methyldopa-induced autoimmune hemolytic anemia does not have typical features and the severity of symptoms ...
Charalampos Grigoriadis, Aliki Tympa, Angelos Liapis, Dimitrios Hassiakos, Panagiotis Bakas   +4 more
doaj   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi, Alphonse Charbel, Jan Pfeiffenberger, Uta Merle, Jessica Seessle, Theresa Wenz, Christa Flechtenmacher, Patrick Michl, Conrad Rauber   +8 more
wiley   +1 more source

Spectrophotometric Determination of Catecholamines Via Charge Transfer Complexation with Bromanil, Applications to Catecholamine Drug Formulations

Science Journal of University of Zakho, 2013
A simple, sensitive, rapid and low-cost spectrophotometric method for catecholamine (levodopa, methyldopa and dopamine) determination in pure and drug formulations is described.
MAHMOOD A. HASAN
doaj