Results 71 to 80 of about 13,801 (241)
Anticholinergic Medication Burden Scales: A Systematic Review
ABSTRACT Background Anticholinergic burden refers to the cumulative anticholinergic effect of all medications taken by an individual. Anticholinergic burden scales help identify patients at risk of anticholinergic adverse effects and guide prescribing. However, substantial variation exists between scales, with no gold standard identified.
Orla Vennard +4 more
wiley +1 more source
Effects of α-methyldopa on blood pressure in the anaesthetized dog
Intravenous infusion over 1 h of 20 mg kg−1 of α-methyldopa produced hypotension in the anaesthetized dog. The magnitude of this effect was, however, inversely correlated with bodyweight.
P R Blower, R H Poyser, M I Robertson
core +1 more source
The Determinants of Negotiated Pharmaceutical Prices
ABSTRACT We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's ...
Ralph B. Siebert +2 more
wiley +1 more source
Objective: Comparison between Methyldopa and combination of Methyldopa and Nifedipine in terms of mean change in blood pressure in pregnancy induced hypertension.
Zain UlAbidin, Quratulain, Sidra Aslam
core
A simple, rapid and sensitive spectrophotometric method has been developed for the determination of methyldopa in pharmaceutical formulations.
Mara Andréia Gotardo +5 more
doaj +1 more source
Alpha-methyldopa in schizophrenia
Reports a case of a 42-yr-old male schizophrenic in whom, after an overdose of alpha-methyldopa, there was a dramatic and apparently complete resolution of psychotic symptomatology, followed after a few weeks by a sudden return of psychosis.
Gaind, R. +2 more
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The mechanism of the antihypertensive effect of alpha-methyldopa was compared with clonidine by administering equipotent single doses of clonidine (0.2 mg) and alpha-methyldopa (750 mg) to nine hypertensive patients. Plasma noradrenaline was followed for
Adams, E F +7 more
core +1 more source
A Novel Multimodal LC–MS/MS Panel for the Comprehensive Diagnosis of Neurometabolic Disorders in CSF
ABSTRACT Metabolic testing of cerebrospinal fluid (CSF) is essential for early diagnosis of neurometabolic disorders. However, the large number of differential diagnoses, the phenotypic variance within a clinical picture, and the disease rarity complicate targeted metabolic diagnostics.
Stine Christ +8 more
wiley +1 more source
Alpha methyldopa induced hepatotoxicity in pregnancy
We report a case of gestational hepatitis due to alpha-methyldopa and briefly review the literature on alpha-methyldopa-induced hepatotoxicity in pregnancy.
Bolarigowda, Priyadarshini +3 more
core +1 more source
Concentration and pH dependency of α-methyldopa absorption in rat intestine
The intestinal absorption of α-methyldopa from perfused segments of rat intestine was determined. Jejunal and ileal segments were studied at pH 4.5, 6.0 and 7.4 at an α-methyldopa concentration of 0.01 mM, and at pH 6.0 at concentrations of 0.01, 0.10 ...
J B Dressman, A E Merfeld, G L Amidon
core +1 more source

