Results 141 to 150 of about 13,481 (184)

Characterization of a pseudogene for murine methylenetetrahydrofolate reductase

Molecular and Cellular Biochemistry, 2003
Methylenetetrahydrofolate reductase (MTHFR) reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the major carbon donor in the remethylation of homocysteine to methionine. Mild MTHFR deficiency, due to a common variant at nucleotide 677, has been reported to influence risk for several disorders including cardiovascular disease, neural ...
Daniel, Leclerc, Hiba, Darwich-Codore, Rima, Rozen   +2 more
openaire   +2 more sources

General anesthesia and methylenetetrahydrofolate reductase deficiency

Journal of Anesthesia, 2007
Methylenetetrahydrofolate reductase (MTHFR) deficiency is an autosomal recessive disorder with a spectrum of manifestations including neurological symptoms, premature arteriosclerosis, and venous and arterial thrombosis. Most patients are heterozygous for multiple MTHFR substitutions; small minorities are homozygous for mutations at this locus.
Hamilton, Shay, Robert J, Frumento, Alexandra, Bastien   +2 more
openaire   +2 more sources

Methylenetetrahydrofolate reductase variant and schizophrenia/depression

American Journal of Medical Genetics, 1997
Patients with methylenetetrahydrofolate reductase (MTHFR) deficiency often show psychiatric manifestations. Since a common variant of the MTHFR gene, T677(Ala), responsible for the thermolabile MTHFR with less than 50% specific MTHFR activity, has been reported, we examined whether the T677 allele is associated with psychiatric disorders in an ...
T, Arinami, N, Yamada, K, Yamakawa-Kobayashi, H, Hamaguchi, M, Toru   +4 more
openaire   +2 more sources

Methylenetetrahydrofolate reductase polymorphism, folate, and susceptibility to preeclampsia

Journal of the Society for Gynecologic Investigation, 1999
To test the hypothesis that the common missense mutation of 5,10-methylenetetrahydrofolate reductase (MTHFR) (677 C to T, ala to val) is more prevalent among nulliparous preeclamptic women compared with control and transient hypertension of pregnancy patients.
R W, Powers, L A, Minich, D L, Lykins, R B, Ness, W R, Crombleholme, J M, Roberts   +5 more
openaire   +2 more sources

Methylenetetrahydrofolate reductase

2022
Rachel M. Donner, Tyler Parisien
openaire   +1 more source

Radioenzymatic assay for reductive catalysis of N5N10-methylenetetrahydrofolate by methylenetetrahydrofolate reductase

Journal of Biochemical and Biophysical Methods, 2000
Methylenetetrahydrofolate reductase catalyzes the reduction of N(5), N(10)-methylenetetrahydrofolate to N(5)-methyltetrahydrofolate. Because this substrate is unstable and dissociates spontaneously into formaldehyde and tetrahydrofolate, the customary method to assay the catalytic activity of this enzyme has been to measure the oxidation of [14C]N(5 ...
P, Sobti, S P, Rothenberg, E V, Quadros
openaire   +2 more sources

Interactions of adenosylmethionine with methylenetetrahydrofolate reductase

1982
Commercial preparations of AdoMet are isolated from yeast, and the AdoMet has the configuration of the natural diastereoisomer at both the sulfonium pole and the methionyl substituent. However, such preparations are not only contaminated with ninhydrin-positive impurities but also with impurities which absorb light at 260 nm and do not react with ...
S Colette Creveling, Elisa C Krapf, Rowena G Matthews   +2 more
openaire   +1 more source

Methylenetetrahydrofolate Reductase Deficiency

2009
Mark Oette, Marvin J. Stone, Hendrik P. N. Scholl, Peter Charbel Issa, Monika Fleckenstein, Steffen Schmitz-Valckenberg, Frank G. Holz, Olaf Strauss, Jörg-Dieter Schulzke, Michael Fromm, Tommie V. McCarthy, Meinhard Schiller, Stephan Grabbe, Cord Sunderkötter, Gidon Almogy, Avraham I. Rivkind, Hideaki Kato, John W. Finley, John W. Finley, Johannes Uhl, Jürgen Kopitz, Michael Cantz, Philip F. Giampietro, Inga Harting, Nicole I. Wolf, Jürgen Grabbe, Robert J. Beynon, Rosaline C. M. Quinlivan, Caroline A. Sewry, Naoto Kuroda, Cengiz Korkmaz, Anthony J. Bleyer, Thomas C. Hart, Michele Bisceglia, Carlos Galliani, Stefan Pfister, Olaf Witt, Alexander K. C. Leung, Jan Hellemans, Geert Mortier, Marcus Schmitt, Markus Pfister, Hans-Peter Zenner, Markus J. Riemenschneider, Guido Reifenberger, Julian F. B. Mercer, Sharon La Fontaine, Ingrid Moll, Bruce C. Kone, Stephan vom Dahl, Peter E. H. Schwarz, Jiang Li, Volkmar Gieselmann, David Genevieve, Martine Le Merrer, John-John B. Schnog, Victor E. A. Gerdes, Katrin Beyer, Elardus Erasmus, Lodewyk J. Mienie, Jan Bubeník, Jana Šímová, Thorsten Buch, Ansgar Schulz, Irmgard Förster, Shirley Hodgson, Holger Sudhoff, Peter J. Goadsby, Karin Jurkat-Rott, Frank Lehmann-Horn, John Logan, Bernadette McGuinness, Maria Isabel Melaragno, Marcial Francis Galera, Alexander K. C. Leung, Hardally R. Hegde, Hannu Jalanko, Maria Judit Molnar, Danae Liolitsa, Charungthai Dejthevaporn, Michael G. Hanna, Josef Finsterer, Yu-ichi Goto, Lucia K. Ma, Patrick T. S. Ma, Alexander K. C. Leung, Toshio Nishikimi, Patrick T. S. Ma, Siobhan D. Ma, Alexander K. C. Leung, Andrew Rozelle, Eliza F. Chakravarty, Stefan R. Bornstein, Sven Schinner, Marinus Duran, Alexander K. C. Leung, William Lane M. Robson, Christine Liang, Julie V. Schaffer, Claudiu Plesa, Franck E. Nicolini, Alexander K. C. Leung, Eric Sibley, Vinzenz Oji, Heiko Traupe, Damian Miles Bailey, Heimo Mairbäurl, Peter Bärtsch, Alexander K. C. Leung, Alexander A. C. Leung, Justine H. S. Fong, Michael Beck, Silke Hofmann, Leena Bruckner-Tuderman, Dieter Metze, Riikka H. Hämäläinen, Anna-Elina Lehesjoki, Marita Lipsanen-Nyman, Constantine Stratakis, Francesca Marini, Alberto Falchetti, Maria Luisa Brandi, Christian A. Koch, Constantine A. Stratakis, Michael Briggs, Wim Wuyts, Filip Vanhoenacker, Wim Hul, Dieter Metze, Hayrettin Tumani, Kurt Von Figura, Thomas Dierks, Bernhard Schmidt, Luca Busetto, Giuliano Enzi, Thomas Klockgether, Ioannis Stefanidis, Georgios M. Hadjigeorgiou, Georgios M. Hadjigeorgiou, Klaus Zerres, Sabine Rudnik-Schöneborn, Hans-Jürgen Gdynia, Anne-Dorte Sperfeld, Eric P. Hoffman, Rabah Ben Yaou, Gisèle Bonne, Dominique Récan-Budiartha, Peter Hackman, Bjarne Udd, Wolfgang Dietmaier, Arndt Hartmann, Dominique Prié, Caroline Silve, Bernard Grandchamp, Gérard Friedlander, Andrew G. Engel, Andrew G. Engel, Werner Kempf, Reinhard Dummer, Günter Burg, Daniela Cilloni, Giuseppe Saglio, Ulrich S. Schuler, Ulrike Bacher, Claudia Haferlach, Susanne Schnittger, Torsten Haferlach, Alexander K. C. Leung, Reginald S. Sauve, Deepak Kamat, Stephen N. Makoni, Richard L. Sabina, Benjamin D. Tyrrell, Justin A. Ezekowitz, Wolfgang Schillinger, Gerd Hasenfuss, Kevin M. Bonney, David M. Engman, Thomas Klopstock, Friedrich Asmus, Thomas Gasser, Dina J. Zand, Elaine H. Zackai, Thomas Klopstock, Frank Schaeffel, Anders Oldfors, Niklas Darin, Tommy Martinsson, Ursula Knirsch, Gisela Stoltenburg-Didinger, Karin Jurkat-Rott, Frank Lehmann-Horn, Olayinka Raheem, Tiina Suominen, Bjarne Udd   +194 more
openaire   +1 more source

Methylenetetrahydrofolate reductase (NADPH)

1994
D. Schomburg, M. Salzmann, D. Stephan
openaire   +1 more source

Prenatal diagnosis for methylenetetrahydrofolate reductase deficiency

The Journal of Pediatrics, 1983
U, Wendel, U, Claussen, E, Diekmann
openaire   +2 more sources