Results 41 to 50 of about 9,036 (155)

Interactions of Methylenetetrahydrofolate Reductase C677T Polymorphism with Environmental Factors on Hypertension Susceptibility

open access: yesInternational Journal of Environmental Research and Public Health, 2016
Hypertension is considered to be the result of genes, environment, and their interactions. Among them age, sex, tobacco use, alcohol consumption, and being overweight/obesity are well documented environmental determinants, and methylenetetrahydrofolate ...
Shujun Fan   +6 more
semanticscholar   +1 more source

A Meta-Analysis of Association between Methylenetetrahydrofolate Reductase Gene (MTHFR) 677C/T Polymorphism and Diabetic Retinopathy

open access: yesInternational Journal of Environmental Research and Public Health, 2016
Aims: To shed light on the conflicting findings of the association between the methylenetetrahydrofolate reductase gene (MTHFR) 677C/T polymorphism and the risk of diabetic retinopathy (DR), a meta-analysis was conducted. Methods: A predefined search was
Shasha Luo   +3 more
semanticscholar   +1 more source

Impact of Genetic Polymorphism of methylenetetrahydrofolate reductase C677T on Development of Hyperhomocysteinemia and Related Oxidative Changes in Egyptian β-Thalassemia Major Patients

open access: yesPLoS ONE, 2016
Background β-thalasemia major (β-TM) patients often suffer from various vascular complications together with increased oxidative stress. Hyperhomocysteinemia (Hhcy) has been defined as a risk factor for these complications.
Mai A. Abd-Elmawla   +3 more
semanticscholar   +1 more source

Genomvergleich und Effektorcharakterisierung von Rhynchosporium commune [PDF]

open access: yes, 2016
Die Erforschung molekularer Mechanismen der Rhynchosporium-Blattfleckenkrankheit ist essentiell zur Entwicklung von Bekämpfungsstrategien. Die Möglichkeiten zur Untersuchung der Rhynchosporium-Wirts-Interaktion wurden durch Sequenzierung der ...
Penselin, Daniel
core   +1 more source

Homocysteine related Nutritional and Genetic Risk Factors for Human Congenital Heart Defects [PDF]

open access: yes, 2007
Congenital heart defects (CHDs) belong to the most common group of major congenital malformations in newborns. Most CHDs are considered complex diseases with a multifactorial aetiology, which are thought to result from interactions between genetic and ...
Verkleij-Hagoort , A.C. (Anna)
core  

Folate related risk factors and orofacial clefting in human: epidemiological and biological studies [PDF]

open access: yes, 2011
__Abstract__ Orofacial clefting (OFC) is a group of congenital malformations characterized by closure defects of the lip, jaw and/or palate. In general, three subgroups of OFC are distinguished, e.g., isolated clefts of the lip or the palate and ...
Bliek, B.J.B. (Bram)
core   +1 more source

Insights into Severe 5,10‐Methylenetetrahydrofolate Reductase Deficiency: Molecular Genetic and Enzymatic Characterization of 76 Patients

open access: yesHuman Mutation, 2015
5,10‐Methylenetetrahydrofolate reductase (MTHFR) deficiency is the most common inherited disorder of folate metabolism and causes severe hyperhomocysteinaemia.
P. Burda   +14 more
semanticscholar   +1 more source

Computing Network of Diseases and Pharmacological Entities through the Integration of Distributed Literature Mining and Ontology Mapping [PDF]

open access: yes, 2011
The proliferation of -omics (such as, Genomics, Proteomics) and -ology (such as, System Biology, Cell Biology, Pharmacology) have spawned new frontiers of research in drug discovery and personalized medicine.
Faisal, Fazle Elahi
core   +1 more source

Glycollate metabolism in detached wheat leaves [PDF]

open access: yes, 1976
Imperial Users ...
Kumarasinghe, Kumarasinghege Saliya   +1 more
core  

Mulecular investigation of mediterranean glucose-6-phosphate dehidrogenase in North West of Iran [PDF]

open access: yes
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme deficiency affecting more than 400 million people worldwide.This enzyme catalyse the first step in pentose phosphate pathway (conversion of glucose-6-phosphate to 6 ...
امانی, فیروز   +4 more
core  

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