Results 31 to 40 of about 107,807 (121)

Overall and stratified meta-analyses of the association between methylenetetrahydrofolate reductase polymorphism 677C→T and risk of type 2 diabetes mellitus.

, 2013
Overall and stratified meta-analyses of the association between methylenetetrahydrofolate reductase polymorphism 677C→T and risk of type 2 diabetes mellitus.
Le-Qun Li (179464), A. Chapin Rodríguez (453949), Jian-Hong Zhong (179419), Na-Na Yang (453950)   +3 more
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Methylenetetrahydrofolate reductase, MTHFR, polymorphisms and predisposition to different multifactorial disorders [PDF]

, 2017
Gene polymorphisms involved in homocysteine-methionine pathway result in hyperhomocysteinemia, a predisposing condition to several diseases. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate and homocysteine metabolism.
BARALDI, OLGA, Chiara Zannini, Gaetano La Manna, CUNA, VANIA, Vilma Mantovani, MANTOVANI, VILMA, Carlotta Pia Cristalli, Giorgia Comai, Giuseppe Cianciolo, Niccolò Natali, LA MANNA, GAETANO, Vania Cuna, CRISTALLI, CARLOTTA PIA, CIANCIOLO, GIUSEPPE, Olga Baraldi, Maria Cappuccilli, CAPPUCCILLI, MARIA, COMAI, GIORGIA, Natali, Niccolò, ZANNINI, CHIARA   +19 more
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Thermolabile methylenetetrahydrofolate reductase enzyme genotype is frequent in type 2 diabetic patients with normal fasting homocysteine levels

, 2005
Objective. To investigate the plasma homocysteine concentrations with regard to nutritional, metabolic and genetic factors and to find out the frequency and impact of thermolabile methylenetetrahydrofolate reductase (T-MTHFR) polymorphism in patients ...
E. TUNCBILEK, M. ALIKASIFOGLU, N. B. TUTUNCU, Erbas, T, T. ERBAS, Tuncbilek, E, Alikasifoglu, M, Tutuncu, NB   +7 more
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Antisense Inhibition of Methylenetetrahydrofolate Reductase Reduces Cancer Cell Survival In vitro and Tumor Growth In vivo

, 2005
Many cancer lines are methionine dependent and decrease proliferation when methionine supply is limited. Methylenetetrahydrofolate reductase (MTHFR) generates the folate derivative for homocysteine remethylation to methionine.
Stankova, Jitka, Rozen, Rima, Shang, Jijun, J. Stankova   +3 more
core   +1 more source

Supplementary Tables 1-3 from Folate Intake along with Genetic Polymorphisms in Methylenetetrahydrofolate Reductase and Thymidylate Synthase in Patients with Advanced Gastric Cancer

, 2010
Supplementary Tables 1-3 from Folate Intake along with Genetic Polymorphisms in Methylenetetrahydrofolate Reductase and Thymidylate Synthase in Patients with Advanced Gastric ...
Kazuo Tajima (152656), Hidemi Ito (181434), Takakazu Kawase (341461), Keitaro Matsuo (73893), Tomoya Yokota (5237633), Satoyo Hosono (500650), Seiji Ito (229086), Hiroki Kawai (1603030), Akira Sawaki (14968602), Kei Muro (3473336), Daisuke Takahari (3473351), Kohei Shitara (5852318), Hideo Tanaka (42339), Masahiro Tajika (8735229), Takashi Shibata (5185469), Miki Watanabe (29882), Yasushi Yatabe (245392), Takashi Ura (3473366)   +17 more
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Association of Methylenetetrahydrofolate Reductase Gene rs1801133 Polymorphism and Controlling Nutritional Status (CONUT) Score with Colorectal Cancer Susceptibility [PDF]

Zhuoxin Zhang,1 Zuguang Wu,1 Yuwen Zeng,1 Yunlin Li,1 Yingchuan Feng,1 Zhen Gao,1 Yijin Chen2 1Department of Gastrointestinal Surgery, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 2Department of Gastroenterology, Meizhou People’s ...
Wu Z, Li Y, Zhang Z, Feng Y, Gao Z, Chen Y, Zeng Y   +6 more
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Evaluation of c677t and a1298c polymorphism of the methylenetetrahydrofolate reductase gene as a maternal risk factor for trisomy 21 (a monocentric study)

, 2017
Aim: To assess the risk for trisomy 21 in children, depending on the polymorphisms C677T and A1298C of the methylenetetrahydrofolate reductase (MTHFR) gene in ...
Nicolaescu Radu, Grigorescu-Sido Paula, Lazea Cecilia, Popp Radu Anghel, Bucerzan Simona, Vlad Raluca Maria   +5 more
core   +1 more source

Comparison of different types of twin pregnancies in terms of obstetric and perinatal outcomes: association of vanished twins with methylenetetrahydrofolate reductase (MTHFR) polymorphism(s).

, 2018
Vanished twin (VT) has been associated with poor perinatal outcomes. Our research aimed to investigate the outcomes of pregnancies with vanished twin and its possible association with methylenetetrahydrofolate reductase (MTHFR ...
Yurdakök, Murat, Gumruk, Fatma, Ozek, Murat Aykut, Orgul, Gokcen, Karaagaoglu, Ergun, Beksac, M Sinan, BEKSAÇ, MEHMET SİNAN   +6 more
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Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia in Budd-Chiari syndrome and portal vein thrombosis: A systematic review and meta-analysis of observational studies

, 2014
A systematic review and meta-analysis were conducted to explore the role of the methylenetetrahydrofolate reductase (MTHFR) C677T gene mutation and hyperhomocysteinemia in patients with Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT)
De Stefano, Valerio
core   +1 more source

Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population

, 2004
Background: Hyperhomocysteinaemia is a common finding in a wide variety of pathological conditions that exhibit endothelial disturbances. In the pathogenesis of pre-eclampsia, endothelial cell activation or dysfunction has been proposed as a central ...
Gurdol, Figen Melek, Yılmaz, H, İşbilen, Elif, İsbir, TURGAY, Unlucerci, Yaşar Meryem Yeşim   +4 more
core   +1 more source