Results 101 to 110 of about 5,012,650 (270)

Levodopa‐Carbidopa Intestinal Gel in an Outpatient Setting: A 10‐Year Experience

Movement Disorders Clinical Practice, EarlyView.
Alessandro Magliozzi, Nicholas Feugas, Yu Yan Poon, Taline Naranian, Louis Liu, Yvonne Tse, Anthony E. Lang, Alfonso Fasano   +7 more
wiley   +1 more source

Vapor pressures of substituted polycarboxylic acids are much lower than previously reported [PDF]

, 2013
The partitioning of compounds between the aerosol and gas phase is a primary focus in the study of the formation and fate of secondary organic aerosol. We present measurements of the vapor pressure of 2-methylmalonic (isosuccinic) acid, 2-hydroxymalonic (
Huisman, A. J., Krieger, U. K., Marcolli, C., Peter, T., Zuend, A.   +4 more
core   +2 more sources

Subacute Painful Axonal Polyneuropathy Associated with Foslevodopa/Foscarbidopa Subcutaneous Infusion in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Aukusti Valli, Filip Scheperjans
wiley   +1 more source

Randomized Open‐Label Clinical Trial Comparing Prednisolone and Cyclosporine With a Nonrandomized Active Control for Treating Presumed Chronic Pancreatitis in Cats

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Current management for chronic pancreatitis in cats is largely symptomatic. Anecdotal reports suggest that immunomodulatory treatment can be helpful in some cases, but limited data is available. Objectives Compare the effects of symptomatic treatments alone, an immunosuppressive dosage of prednisolone, or modified cyclosporine on ...
Yu‐An Wu, Jonathan A. Lidbury, Samiran Sinha, Jörg M. Steiner   +3 more
wiley   +1 more source

A Prospective Study on Serum Methylmalonic Acid and Homocysteine in Pregnant Women

Nutrients, 2016
This study aimed to investigate serum methylmalonic acid (MMA) and homocysteine levels and to assess their effects on pregnancy and neonatal outcomes.
R. Choi, S. Choi, Yaeji Lim, Y. Cho, Hye Jeong Kim, S. Kim, J. Chung, S. Oh, Soo-Youn Lee   +8 more
semanticscholar   +1 more source

Causes of and diagnostic approach to methylmalonic acidurias [PDF]

, 2018
Summary: Several mutant genetic classes that cause isolated methylmalonic acidurias (MMAuria) are known based on biochemical, enzymatic and genetic complementation analysis. The mut0 and mut− defects result from deficiency of MMCoA mutase apoenzyme which
Baumgartner, M., Fowler, B., Leonard, J.
core  

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Clinical picture and treatment effects in 5 patients with Methylmalonic aciduria related to MMAA mutations

Molecular Genetics and Metabolism Reports, 2020
Introduction: Methylmalonic Aciduria (MMA) is a heterogeneous group of rare diseases leading to accumulation of methylmalonic acid in body fluids. One of the causes of the disease is the methylmalonic aciduria, cblA type (cblA – type MMA), conditioned by
Dorota Wesół-Kucharska, Magdalena Kaczor, Magdalena Pajdowska, Ewa Ehmke vel Emczyńska-Seliga, Anna Bogdańska, Dariusz Kozłowski, Dorota Piekutowska-Abramczuk, Elżbieta Ciara, Dariusz Rokicki   +8 more
doaj  

Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. [PDF]

, 2016
Using 3D organotypic rat brain cell cultures in aggregates we recently identified 2-methylcitrate (2-MCA) as the main toxic metabolite for developing brain cells in methylmalonic aciduria.
Ballhausen, D., Braissant, O., Cudré-Cung, H.P., do Vale-Pereira, S., Henry, H., Ivanisevic, J., Remacle, N., Tavel, D., Zavadakova, P.   +8 more
core   +1 more source

Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults

Annals of Neurology, Volume 97, Issue 6, Page 1190-1204, June 2025.
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard, Ahmed Abdelhak, Rowan Saloner, Simone Sacco, Shivany C. Montes, Frederike C. Oertel, Christian Cordano, Nour Jabassini, Kirtana Ananth, Apraham Gomez, Azeen Keihani, Makenna Chapman, Sree Javvadi, Shikha Saha, Adam Staffaroni, Christopher Songster, Martin Warren, John W. Boscardin, Joel Kramer, Bruce Miller, Joshua W. Miller, Ralph Green, Ari J. Green   +22 more
wiley   +1 more source