Results 11 to 20 of about 10,813 (223)

Correlation between toxic organic acid fluctuations and neurodevelopment in patients with methylmalonic acidemia

Orphanet Journal of Rare Diseases
Background Methylmalonic acidemia (MMA) is a rare autosomal recessive disorder, that causes multisystem damage by accumulating toxic metabolites. These metabolites, particularly affecting nerve cells, contribute to suboptimal neurodevelopment in MMA ...
I.-Chih Ling, Dau-Ming Niu, Chia-Feng Yang, Cheng-Yu Lee, Sheng-Bin Liang, Yann-Jang Chen   +5 more
doaj   +2 more sources

T- and pH-Dependent Hydroxyl-Radical Reaction Kinetics of Lactic Acid, Glyceric Acid, and Methylmalonic Acid in the Aqueous Phase. [PDF]

J Phys Chem A
Hu Y, Zhang Y, Wen L, Schaefer T, Herrmann H.   +4 more
europepmc   +2 more sources

Association between oxidative balance score and cardiovascular diseases: mediating analysis of methylmalonic acid based on the NHANES database. [PDF]

Front Nutr
Yang X, Zhang Z, Ye F, Liu P, Peng B, Wang T.   +5 more
europepmc   +2 more sources

Mitochondria-derived methylmalonic acid aggravates ischemia-reperfusion injury by activating reactive oxygen species-dependent ferroptosis. [PDF]

Cell Commun Signal
Guo J, Wang S, Wan X, Liu X, Wang Z, Liang C, Zhang Z, Wang Y, Yan M, Wu P, Fang S, Yu B.   +11 more
europepmc   +3 more sources

FOXA2-initiated transcriptional activation of INHBA induced by methylmalonic acid promotes pancreatic neuroendocrine neoplasm progression. [PDF]

Cell Mol Life Sci
Hu C, Ye M, Bai J, Liu P, Lu F, Chen J, Xu Y, Yan L, Yu P, Xiao Z, Gu D, Xu L, Tian Y, Tang Q.   +13 more
europepmc   +3 more sources

Association between methylmalonic acid and prevalence of depression in US adults: evidence from NHANES 2011-2014. [PDF]

Eur J Psychotraumatol
Li S, Nan W, Peng Z, Huang Q, Chen Q, He B.   +5 more
europepmc   +2 more sources

The mechanism of enterogenous toxin methylmalonic acid aggravating calcium-phosphorus metabolic disorder in uremic rats by regulating the Wnt/β-catenin pathway. [PDF]

Mol Med
Fan X, Li J, Gao Y, Li L, Zhang H, Bi Z.
europepmc   +2 more sources

Case Report: A Case of Late-Onset Combined Methylmalonic Acidemia and Hyperhomocysteinemia Induced by a Vegetarian Diet

Frontiers in Pediatrics, 2022
Methylmalonic acidemia is a rare autosomal recessive metabolic disease. However, because of the atypical clinical symptoms, the type of late-onset methylmalonic academia is often misdiagnosed.
Bei Xu, Lihong Zhang, Qiang Chen, Yajuan Wang, Yahong Peng, Hui Tang   +5 more
doaj   +1 more source

The isolation of methylmalonic acid from rat urine [PDF]

Biochemical Journal, 1936
Alfred Aaron Levi, Eric Boyland
openaire   +4 more sources

Prenatal Diagnosis of Two Common Inborn Errors of Metabolism by Genetic and Mass Spectrometric Analysis of Amniotic Fluid

Frontiers in Pediatrics, 2022
Methylmalonic acidaemia (MMA) and ornithine transcarbamylase deficiency (OTCD) are both intoxication-type inborn errors of metabolism (IEM). Presently, genetic testing is the primary method for prenatally diagnosing these diseases.
Congcong Shi, Sitao Li, Yu Gao, Zhirong Deng, Hu Hao, Xin Xiao   +5 more
doaj   +1 more source