Results 221 to 230 of about 5,012,650 (270)
Some of the next articles are maybe not open access.
Journal of Materials Chemistry C, 2023
This work focuses on the design of multifunctional lanthanide MOFs platform for smart sensing of methylmalonic acid (MMA) and anti-counterfeiting applications. The platform enables intuitive detection of MMA in urine to further infer vitamin B12 levels.
Xiangmei Lu +3 more
semanticscholar +1 more source
This work focuses on the design of multifunctional lanthanide MOFs platform for smart sensing of methylmalonic acid (MMA) and anti-counterfeiting applications. The platform enables intuitive detection of MMA in urine to further infer vitamin B12 levels.
Xiangmei Lu +3 more
semanticscholar +1 more source
CrysteEngComm, 2023
Developing high-performance sensing materials for the sensitive detection of methylmalonic acid (MMA) in biological sample is pretty important for the early diagnosis, recognition and treatment of related diseases.
Rong Luo +6 more
semanticscholar +1 more source
Developing high-performance sensing materials for the sensitive detection of methylmalonic acid (MMA) in biological sample is pretty important for the early diagnosis, recognition and treatment of related diseases.
Rong Luo +6 more
semanticscholar +1 more source
Serum methylmalonic acid in uraemia
Scandinavian Journal of Clinical and Laboratory Investigation, 1992During a 3 month period we measured serum methylmalonic acid concentrations monthly in 37 patients, all on chronic haemodialysis because of end-stage kidney disease. Concentrations of methylmalonic acid in serum were above the upper reference limit in 36 of the 37 subjects.
K. Rasmussen +2 more
openaire +3 more sources
Methylmalonic Acid Excretion Studies
British Journal of Haematology, 1973Summary. Oral valine and isoleucine were equally effective in producing an increased urinary excretion of methylmalonic acid (MMA) in vitamin B12 deficiency but oral MMA itself, methionine and leucine were unsatisfactory.MMA excretion was increased in 16 out of 23 patients with vitamin B12 deficiency after valine and/or isoleucine loading but remained
I. Chanarin +3 more
openaire +3 more sources
Methylmalonic acid — an endogenous toxin?
Cellular and Molecular Life Sciences, 2005Methylmalonic acid was previously considered as major neurotoxin in methylmalonic acidurias. In contrast, recent studies support the notion that other metabolites deriving from propionyl-coenzyme A, inducing synergistic inhibition of mitochondrial energy metabolism, are more important than methylmalonic acid to understand the neuropathogenesis of this ...
Jürgen G. Okun, Stefan Kölker
openaire +2 more sources
Colorimetric Method for Determination of Urinary Methylmalonic Acid [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1979 The colorimetric method for the determination of methylmalonic acid by coupling with diazotised p-nitroaniline has been re-examined. Extraction of the diazotised product into amyl alcohol and tetra-methyl ammonium hydroxide considerably increases its stability and sensitivity and reduces background absorbance.
W. Taylor, A. Westwood, G. Davies
openaire +2 more sources
Journal of Medical Screening, 2020
Objectives Determination of methylmalonic acid, 2-methylcitric acid, and total homocysteine in dried blood spots by liquid chromatography–tandem mass spectrometry has usually been used as a second-tier test to improve performance of newborn screening for
Zhenzhen Hu +7 more
semanticscholar +1 more source
Objectives Determination of methylmalonic acid, 2-methylcitric acid, and total homocysteine in dried blood spots by liquid chromatography–tandem mass spectrometry has usually been used as a second-tier test to improve performance of newborn screening for
Zhenzhen Hu +7 more
semanticscholar +1 more source
Methylmalonic Acid in Dialysis Patients
Hemodialysis International, 2003Propionyl-CoA is a common product of metabolism of essential AA (Val, Thr, Leu, Ile), fatty acids and cholesterol and is further metabolised enzymatically to methyl-malonyl CoA, which is further isomerised to succinyl CoA. Because of the common cofactor (cobalamin) methylmalonic acid (Mma) can serve as an early marker of functional cobalamin deficiency.
F. Pehal +3 more
openaire +2 more sources
Methylmalonic acid values in healthy Dutch children
European Journal of Nutrition, 2007Plasma methylmalonic acid (MMA) is a specific marker for functional cobalamin deficiency. This deficiency can give rise to non-specific but serious symptoms in childhood such as developmental delay, convulsions and failure to thrive and may even lead to irreversible neurological damage.To analyse plasma MMA concentrations in Dutch children and to ...
Hogeveen, M. +5 more
openaire +5 more sources
Pediatrics, 1973
Methylmalonate studies have led to some understanding of vitamin B12 metabolism as well as certain inborn errors of metabolism. These, in turn, have served as models of a group of diseases related to acidosis, so that the study of organic aciduria at present is similar to that of amino aciduria 20 years ago.
openaire +3 more sources
Methylmalonate studies have led to some understanding of vitamin B12 metabolism as well as certain inborn errors of metabolism. These, in turn, have served as models of a group of diseases related to acidosis, so that the study of organic aciduria at present is similar to that of amino aciduria 20 years ago.
openaire +3 more sources