Results 21 to 30 of about 5,012,650 (270)

Methylmalonic Acid and Vitamin B12 in Patients with Heart Failure.

Hellenic Journal of Cardiology, 2019
Vitamin B12 deficiency among patients with heart failure (HF) may have been underestimated. High serum levels of methylmalonic acid (MMA) have been identified in several studies as an early indicator of vitamin B12 deficiency. Furthermore, MMA seems to constitute a biomarker of oxidative stress and mitochondrial dysfunction.
K. Polytarchou, Y. Dimitroglou, D. Varvarousis, N. Christodoulis, C. Psachoulia, C. Pantziou, I. Mourouzis, C. Pantos, A. Manolis   +8 more
semanticscholar   +5 more sources

Colorimetric method for estimating methylmalonic acid in urine. [PDF]

Journal of Clinical Pathology, 1968
A Green
openalex   +4 more sources

Correlation between toxic organic acid fluctuations and neurodevelopment in patients with methylmalonic acidemia

Orphanet Journal of Rare Diseases
Background Methylmalonic acidemia (MMA) is a rare autosomal recessive disorder, that causes multisystem damage by accumulating toxic metabolites. These metabolites, particularly affecting nerve cells, contribute to suboptimal neurodevelopment in MMA ...
I.-Chih Ling, Dau-Ming Niu, Chia-Feng Yang, Cheng-Yu Lee, Sheng-Bin Liang, Yann-Jang Chen   +5 more
doaj   +2 more sources

Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress, predicts all-cause and cardiovascular mortality in the general population. [PDF]

Redox Biol, 2020
Wang S, Liu Y, Liu J, Tian W, Zhang X, Cai H, Fang S, Yu B.   +7 more
europepmc   +2 more sources

Healthy Eating Index-2015, a protective factor for mitochondria-derived methylmalonic acid in the low poverty/income ratio with chronic kidney diseases: results from NHANES 2011-2014. [PDF]

Ren Fail
Xiao Y, Yang Y, Zhang H, Wang J, Lin T, Bai Y.   +5 more
europepmc   +2 more sources

Association analysis between circulating methylmalonic acid and cognitive performance: a population-based cross-sectional study. [PDF]

Front Neurol
Wang C, Guo W, Xue Y, Xu L.
europepmc   +2 more sources

Exploring the relationship between vitamin B12, methylmalonic acid levels and all-cause mortality in heart failure populations: insights from the NHANES database. [PDF]

Front Nutr
Yu W, Wang Y, Zhou Y, Wu D.
europepmc   +2 more sources

Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2‐cohort study

Journal of Internal Medicine, 2023
Elevated plasma methylmalonic acid (MMA) is reported in patients with established coronary heart disease (CHD) and is considered a marker of vitamin B12 deficiency. Moreover, MMA‐dependent reactions have been linked to alterations in mitochondrial energy
I. Dhar, Vegard Lysne, A. Ulvik, G. Svingen, E. Pedersen, E. Bjørnestad, T. Olsen, Robert A. Borsholm, J. Laupsa-Borge, P. Ueland, G. Tell, R. Berge, G. Mellgren, K. Bønaa, O. Nygård   +14 more
semanticscholar   +1 more source

Association between oxidative balance score and cardiovascular diseases: mediating analysis of methylmalonic acid based on the NHANES database. [PDF]

Front Nutr
Yang X, Zhang Z, Ye F, Liu P, Peng B, Wang T.   +5 more
europepmc   +2 more sources

Case Report: A Case of Late-Onset Combined Methylmalonic Acidemia and Hyperhomocysteinemia Induced by a Vegetarian Diet

Frontiers in Pediatrics, 2022
Methylmalonic acidemia is a rare autosomal recessive metabolic disease. However, because of the atypical clinical symptoms, the type of late-onset methylmalonic academia is often misdiagnosed.
Bei Xu, Lihong Zhang, Qiang Chen, Yajuan Wang, Yahong Peng, Hui Tang   +5 more
doaj   +1 more source