Results 11 to 20 of about 12,925 (176)

Methylmercury inhibits prolactin release in a cell line of pituitary origin [PDF]

Brazilian Journal of Medical and Biological Research, 2015
Heavy metals, such as methylmercury, are key environmental pollutants that easily reach human beings by bioaccumulation through the food chain. Several reports have demonstrated that endocrine organs, and especially the pituitary gland, are potential ...
L.A.L. Maués, B.M. Macchi, M.E. Crespo-López, L.E. Nasciutti, D.L.W. Picanço-Diniz, J. Antunes-Rodrigues, J.L.M. do Nascimento   +6 more
doaj   +3 more sources

Arctic methylmercury cycling

Science of The Total Environment, 2022
Anthropogenic mercury (Hg) undergoes long-range transport to the Arctic where some of it is transformed into methylmercury (MeHg), potentially leading to high exposure in some Arctic inhabitants and wildlife. The environmental exposure of Hg is determined not just by the amount of Hg entering the Arctic, but also by biogeochemical and ecological ...
Jonsson, Sofi, Mastromonaco, Michelle Nerentorp, Wang, Feiyue, Bravo, Andrea G., Cairns, Warren R.L., Chételat, John, Douglas, Thomas A., Lescord, Gretchen, Ukonmaanaho, Liisa, Heimbürger-Boavida, Lars-Eric   +10 more
openaire   +7 more sources

Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia

Scientific Reports, 2021
We recently found that tumor necrosis factor-α (TNF-α) may be involved in neuronal cell death induced by methylmercury in the mouse brain. Here, we examined the cells involved in the induction of TNF-α expression by methylmercury in the mouse brain by in
Takashi Toyama, Takayuki Hoshi, Takuya Noguchi, Yoshiro Saito, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang   +6 more
doaj   +1 more source

Changes in erythrocyte methylmercury among women during pregnancy: a monocentric survey and comparison study

Zhongguo gonggong weisheng, 2022
Objective To investigate changes in peripheral erythrocyte methylmercury among pregnant women during different gestational periods and the methylmercury in neonatal umbilical cord blood erythrocyte.
Xing CHEN, Jia-yao LUO, Huan CHEN, Xi CHEN   +3 more
doaj   +1 more source

Glia and Methylmercury Neurotoxicity [PDF]

Journal of Toxicology and Environmental Health, Part A, 2012
Methylmercury (MeHg) is a global environmental pollutant with significant adverse effects on human health. As the major target of MeHg, the central nervous system (CNS) exhibits the most recognizable poisoning symptoms. The role of the two major nonneuronal cell types, astrocytes and microglia, in response to MeHg exposure was recently compared.
Mingwei, Ni, Xin, Li, João B T, Rocha, Marcelo, Farina, Michael, Aschner   +4 more
openaire   +2 more sources

Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions

Brazilian Journal of Medical and Biological Research, 2011
We evaluated the potential neuroprotective effect of 1-100 µM of four organoselenium compounds: diphenyl diselenide, 3’3-ditri-fluoromethyldiphenyl diselenide, p-methoxy-diphenyl diselenide, and p-chloro-diphenyl diselenide, against methylmercury ...
D.F. Meinerz, M.T. de Paula, B. Comparsi, M.U. Silva, A.E. Schmitz, H.C. Braga, P.S. Taube, A.L. Braga, J.B.T. Rocha, A.L. Dafre, M. Farina, J.L. Franco, T. Posser   +12 more
doaj   +3 more sources

The Nuclear Protein HOXB13 Enhances Methylmercury Toxicity by Inducing Oncostatin M and Promoting Its Binding to TNFR3 in Cultured Cells

Cells, 2019
Homeobox protein B13 (HOXB13), a transcription factor, is related to methylmercury toxicity; however, the downstream factors involved in enhancing methylmercury toxicity remain unknown.
Takashi Toyama, Sidi Xu, Ryo Nakano, Takashi Hasegawa, Naoki Endo, Tsutomu Takahashi, Jin-Yong Lee, Akira Naganuma, Gi-Wook Hwang   +8 more
doaj   +1 more source

Community-driven research in the canadian arctic: dietary exposure to methylmercury and gastric health outcomes

International Journal of Circumpolar Health, 2021
Indigenous Arctic Canadians have a higher prevalence of gastric neoplasms relative to North Americans of European ancestry. We investigated the hypothesis that low-dose methylmercury exposure from eating fish/whale increases the risk of gastric cancer in
Emily V. Walker, Safwat Girgis, Yan Yuan, Karen J. Goodman   +3 more
doaj   +1 more source

Scientific Opinion on the risk for public health related to the presence of mercury and methylmercury in food [PDF]

EFSA Journal, 2012
EFSA was asked by the European Commission to consider new developments regarding inorganic mercury and methylmercury toxicity and evaluate whether the Joint FAO/WHO Expert Committee on Food Additives (JECFA) provisional tolerable weekly intakes for ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

Patterns of fish and whale consumption in relation to methylmercury in hair among residents of Western Canadian Arctic communities

BMC Public Health, 2020
Background Methylmercury contamination of the environment represents a substantial environmental health concern. Human exposure to methylmercury occurs primarily through consumption of fish and marine mammals.
Emily V. Walker, Yan Yuan, Safwat Girgis, Karen J. Goodman   +3 more
doaj   +1 more source