Structure of recombinant formate dehydrogenase from Methylobacterium extorquens (MeFDH1) [PDF]
Scientific Reports, 2023 Formate dehydrogenase (FDH) is critical for the conversion between formate and carbon dioxide. Despite its importance, the structural complexity of FDH and difficulties in the production of the enzyme have made elucidating its unique physicochemical ...
Junsun Park +6 more
doaj +4 more sources
Co-consumption of methanol and succinate by Methylobacterium extorquens AM1. [PDF]
PLoS ONE, 2012 Methylobacterium extorquens AM1 is a facultative methylotrophic Alphaproteobacterium and has been subject to intense study under pure methylotrophic as well as pure heterotrophic growth conditions in the past.
Rémi Peyraud +4 more
doaj +9 more sources
A novel pair of inducible expression vectors for use in Methylobacterium extorquens. [PDF]
BMC Res Notes, 2013 Background: Due to the ever increasing use of diverse microbial taxa in basic research and industrial settings, there is a growing need for genetic tools to alter the physiology of these organisms. In particular, there is a dearth of inducible expression
Chubiz LM +3 more
europepmc +7 more sources
Metabolic engineering of Methylobacterium extorquens AM1 for the production of butadiene precursor [PDF]
Microbial Cell Factories, 2018 Background Butadiene is a platform chemical used as an industrial feedstock for the manufacture of automobile tires, synthetic resins, latex and engineering plastics. Currently, butadiene is predominantly synthesized as a byproduct of ethylene production
Jing Yang +10 more
doaj +2 more sources
Hopanoid-free Methylobacterium extorquens DM4 overproduces carotenoids and has widespread growth impairment. [PDF]
PLoS ONE, 2017 Hopanoids are sterol-like membrane lipids widely used as geochemical proxies for bacteria. Currently, the physiological role of hopanoids is not well understood, and this represents one of the major limitations in interpreting the significance of their ...
Alexander S Bradley +7 more
doaj +2 more sources
Production of functionalized polyhydroxyalkanoates by genetically modified
Microbial Cell Factories, 2010 Background Methylotrophic (methanol-utilizing) bacteria offer great potential as cell factories in the production of numerous products from biomass-derived methanol. Bio-methanol is essentially a non-food substrate, an advantage over sugar-utilizing cell
Miguez Carlos B +5 more
doaj +7 more sources
Methylobacterium extorquens PA1 utilizes multiple strategies to maintain formaldehyde homeostasis during methylotrophic growth. [PDF]
PLoS GeneticsMetabolic homeostasis is a central organizing principle of physiology whereby dynamic processes work to maintain a balanced internal state. Highly reactive essential metabolites are ideally maintained at equilibrium to prevent cellular damage.
Zachary T Hying +4 more
doaj +2 more sources
Production of 3-hydroxypropionic acid in engineered Methylobacterium extorquens AM1 and its reassimilation through a reductive route [PDF]
Microbial Cell Factories, 2017 Background 3-Hydroxypropionic acid (3-HP) is an important platform chemical, serving as a precursor for a wide range of industrial applications such as the production of acrylic acid and 1,3-propanediol.
Yi-Ming Yang +8 more
doaj +2 more sources
Continuous Culture Adaptation of Methylobacterium extorquens AM1 and TK 0001 to Very High Methanol Concentrations [PDF]
Frontiers in Microbiology, 2019 The bio-economy relies on microbial strains optimized for efficient large scale production of chemicals and fuels from inexpensive and renewable feedstocks under industrial conditions.
Sophia Belkhelfa +14 more
doaj +2 more sources
A catalytic role of XoxF1 as La3+-dependent methanol dehydrogenase in Methylobacterium extorquens strain AM1. [PDF]
PLoS ONE, 2012 In the methylotrophic bacterium Methylobacterium extorquens strain AM1, MxaF, a Ca(2+)-dependent methanol dehydrogenase (MDH), is the main enzyme catalyzing methanol oxidation during growth on methanol.
Tomoyuki Nakagawa +7 more
doaj +4 more sources