Aromatic acid metabolism in Methylobacterium extorquens reveals interplay between methylotrophic and heterotrophic pathways [PDF]
Applied and Environmental MicrobiologyEfforts toward microbial conversion of lignin to value-added products face many challenges because lignin’s methoxylated aromatic monomers release toxic C1 byproducts such as formaldehyde.
Norma Cecilia Martinez-Gomez
exaly +4 more sources
Characterization of C30 carotenoid and identification of its biosynthetic gene cluster in Methylobacterium extorquens AM1 [PDF]
Synthetic and Systems Biotechnology, 2023 Methylobacterium species, the representative bacteria distributed in phyllosphere region of plants, often synthesize carotenoids to resist harmful UV radiations.
Xu-Hua Mo +6 more
doaj +2 more sources
Engineered Methylobacterium extorquens grows well on methoxylated aromatics due to its formaldehyde metabolism and stress response [PDF]
mSphereLignin is a vast yet underutilized source of renewable energy. The microbial valorization of lignin is challenging due to the toxicity of its degradation intermediates, particularly formaldehyde.
Akorede L. Seriki +5 more
doaj +2 more sources
Bioelectrochemical conversion of CO2 to value added product formate using engineered Methylobacterium extorquens [PDF]
Scientific Reports, 2018 The conversion of carbon dioxide to formate is a fundamental step for building C1 chemical platforms. Methylobacterium extorquens AM1 was reported to show remarkable activity converting carbon dioxide into formate.
Jungho Jang +2 more
doaj +2 more sources
Multiple σEcfG and NepR Proteins Are Involved in the General Stress Response in Methylobacterium extorquens. [PDF]
PLoS ONE, 2016 In Alphaproteobacteria, the general stress response (GSR) is controlled by a conserved partner switch composed of the sigma factor σ(EcfG), its anti-sigma factor NepR and the anti-sigma factor antagonist PhyR.
Anne Francez-Charlot +4 more
doaj +2 more sources
Genetic and phenotypic comparison of facultative methylotrophy between Methylobacterium extorquens strains PA1 and AM1. [PDF]
PLoS ONE, 2014 Methylobacterium extorquens AM1, a strain serendipitously isolated half a century ago, has become the best-characterized model system for the study of aerobic methylotrophy (the ability to grow on reduced single-carbon compounds).
Dipti D Nayak, Christopher J Marx
doaj +2 more sources
Engineering Terpene Production Pathways in Methylobacterium extorquens AM1 [PDF]
MicroorganismsTerpenes are diverse specialized metabolites naturally found within plants and have important roles in inter-species communication, adaptation and interaction with the environment.
Allison Hurt +3 more
doaj +2 more sources
Structure of recombinant formate dehydrogenase from Methylobacterium extorquens (MeFDH1) [PDF]
Scientific ReportsFormate dehydrogenase (FDH) is critical for the conversion between formate and carbon dioxide. Despite its importance, the structural complexity of FDH and difficulties in the production of the enzyme have made elucidating its unique physicochemical ...
Junsun Park +6 more
doaj +2 more sources
Metabolic engineering of Methylobacterium extorquens AM1 for the production of butadiene precursor [PDF]
Microbial Cell Factories, 2018 Background Butadiene is a platform chemical used as an industrial feedstock for the manufacture of automobile tires, synthetic resins, latex and engineering plastics. Currently, butadiene is predominantly synthesized as a byproduct of ethylene production
Jing Yang +10 more
doaj +2 more sources
Persistence preserves phenotypic heterogeneity in non-genetic formaldehyde resistance in Escherichia coli [PDF]
BMC Research NotesObjectives Recently, it was discovered that Methylobacterium extorquens possesses a spectrum of phenotypic states conferring non-genetic resistance to formaldehyde.
Isaiah D. Jordan +3 more
doaj +2 more sources