Results 121 to 130 of about 45,414 (227)

Methylphenidate hydrochloride and asymptomatic ocular changes

Psychiatry and Clinical Psychopharmacology, 2021
Objective: To examine cataract formation and assess intraocular pressure (IOP) measurement with Goldmann applanation tonometry in children taking methylphenidate hydrochloride. Methods: Forty children with attention deficit hyperactivity disorder aged
Nagihan Saday Duman, Rahmi Duman, Emel Sari Gokten, Sadik Gorkem Cevik, Ayse Balikci, Neslihan Parmak, Mehmet Erdem Uzun, Sertac Argun Kivanc, Resat Duman   +8 more
doaj  

Testing DAT1 and DRD4 Genes in Attention Deficit Hyperactivity Disorder Using a Wide Spectrum of Neurocognitive Batteries

International Journal of Developmental Neuroscience, Volume 86, Issue 3, May 2026.
This study examined DAT1 and DRD4 VNTR polymorphisms and neurocognitive performance in 336 children and adolescents with ADHD and controls using the CNS Vital Signs battery. DAT1 10R/10R showed no significant effects after adjustment, whereas DRD4 4R/4R was associated with reduced cognitive flexibility. ABSTRACT Attention‐deficit/hyperactivity disorder
Gül Ünsel‐Bolat, Hilmi Bolat, Sema Yıldırım, Semiha Özgül, Akın Tahıllıoğlu, Kemal Utku Yazıcı, Ali Bacanlı, Erhan Parıltay, Duygu Aygüneş‐Jafari, Buket Kosova, Luis Augusto Rohde, Haluk Akın, Eyüp S. Ercan   +12 more
wiley   +1 more source

The Separate or Concurrent Effects of Methylphenidate and Alcohol on Acquisition and Retention of the Morris Water Maze in Adolescent Rats [PDF]

, 2014
Alcohol’s (A) capacity to impair learning and memory has been well documented in the Morris Water Maze (MWM) but few studies have examined methylphenidate’s (MPH) impact on MWM performance (Haidun et al., 2010; Zeise et al., 2007).
Creech, Matthew K., Scott, Lindsay
core   +1 more source

2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot, Forbes D. Porter, Tatiana Bremova‐Ertl, Uma Ramaswami, Caroline Hastings, Bénédicte Héron, Justin Hopkin, Joella Melville, Hernan Amartino, Mireia del Toro, Federica Deodato, Fatih Ezgü, Paul Gissen, James B. Gibson, Can Ficicioglu, Roberto Giugliani, Orna Staretz‐Chacham, Frances Platt, Nathalie Guffon, Kristina Julich, Nikola Kresojević, Anna Lehman, Yann Nadjar, Susanne A. Schneider, Simon Jones, Eugen Mengel, Michel Tchan, Mark Walterfang, Ozlem Goker‐Alpan, Charlotte Dawson, Sandra Cowie, Toni Mathieson, Elizabeth Berry‐Kravis, Marc C. Patterson   +33 more
wiley   +1 more source

Psychostimulant treatment uniquely reduces left uncinate fasciculus microstructural integrity in ADHD youth with a familial risk for bipolar I disorder: a 12‐week DTI study

Journal of Child Psychology and Psychiatry, Volume 67, Issue 5, Page 696-706, May 2026.
Background Bipolar I disorder (BD) is associated with reduced white matter microstructural integrity in the uncinate fasciculus (UF), a primary fiber tract connecting frontolimbic systems. Although familial history for BD, attention‐deficit/hyperactivity disorder (ADHD), and psychostimulants are important risk factors implicated in BD pathoetiology ...
Kun Qin, Wen Chen, Du Lei, Ziyu Zhu, Maxwell J. Tallman, Nanfang Pan, Lisha Zhang, Luis Rodrigo Patino, John A. Sweeney, Melissa P. DelBello, Robert K. McNamara   +10 more
wiley   +1 more source

Engaging students with ADHD in mainstream education : lessons from children, parents and teachers [PDF]

, 2009
The move towards inclusive education in the UK (DfEE 1997; DfEE 2004a), and more recently integrated working (DfES 2003), has resulted in the development of a national framework calling for a change to the way organizations meet the needs of children ...
Hughes, Lesley
core  

Altered spectral patterns of aperiodic electroencephalography in autism

Psychiatry and Clinical Neurosciences, Volume 80, Issue 5, Page 423-431, May 2026.
Aim The altered ratio of neural excitation (E) and inhibition (I) has been proposed to the etiology of autism spectrum disorder (ASD). Previous studies suggested a lower E/I ratio in autistic individuals compared to non‐autistic comparisons (NACs) in specific brain regions.
Yi‐Ling Chien, Ming Hsien Hsieh, Yi‐Hsuan Hsieh, Yi‐Li Tseng   +3 more
wiley   +1 more source

In Search of the Neurobiological Substrates for Social Playfulness in Mammalian Brains

, 2011
Play behavior is a fundamental and intrinsic neurobehavioral process in the mammalian brain. Using rough-and-tumble play in the juvenile rat as a model system to study mammalian playfulness, some of the relevant neurobiological substrates for this ...
Panksepp, Jaak, Siviy, Stephen M.
core   +1 more source

Effect of Methylphenidate on Methadone-Induced Analagesia in Rat

مجله دانشکده پزشکی اصفهان, 2015
Background: A known problem of chronic administration of opioid is tolerance to its analgesic effect. Co-administration of a non-opioid analgesic may help reducing the opiate dose and consequently tolerance and dependency.
Babak Zanjani, Mohammad Raman Moloudi, Esmael Izadpanah, Kambiz Hassanzadeh   +3 more
doaj  

Pulmonary emphysema induced by methylphenidate: experimental study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Methylphenidate is the most widely used drug for treating attention deficit hyperactivity disorder. However, it has important side effects, such as abdominal pain, insomnia, anorexia and loss of appetite, and also some cases of ...
Gabriel Victor Guimarães Rapello, Andréia Antoniolli, Daniel Martins Pereira, Gilberto Facco, Paulo Manuel Pêgo-Fernandes, Rogério Pazetti   +5 more
doaj   +1 more source