Results 71 to 80 of about 40,562 (182)

Daytime sleepiness and BMI exhibit gender and age differences in patients with central disorders of hypersomnolence

Journal of Sleep Research, Volume 34, Issue 3, June 2025.
In a cohort of central disorders of hypersomnolence, specifically women with idiopathic hypersomnia showed a marked subjective daytime sleepiness peak in the early 30s, while the body mass index only started to rise at that age. Better understanding of the pathophysiology of these gender and age‐specific characteristics will support tailored ...
Laura Ferrazzini, Markus Schmidt, Zhongxing Zhang, Ramin Khatami, Yves Dauvilliers, Lucie Barateau, Geert Mayer, Fabio Pizza, Giuseppe Plazzi, Jari K. Gool, Rolf Fronczek, Gert Jan Lammers, Rafael del Rio‐Villegas, Rosa Peraita‐Adrados, Markku Partinen, Sebastiaan Overeem, Karel Sonka, Joan Santamaria, Raphael Heinzer, Francesca Canellas, Antonio Martins da Silva, Birgit Högl, Christian Veauthier, Aleksandra Wierzbicka, Eva Feketeova, Jitka Buskova, Michel Lecendreux, Silvia Miano, Ulf Kallweit, Anna Heidbreder, Claudio L. A. Bassetti, Julia van der Meer   +31 more
wiley   +1 more source

Modafinil dependence: A case with attention-deficit/hyperactivity disorder [PDF]

, 2018
Modafinil is generally known as a drug with low addiction potential. There are few case reports in the literature demonstrating that Modafinil, stated being capable of diminishing symptoms of attention deficit/hyperactivity disorder (ADHD), causes ...
Alaçam, Hüseyin, Başay, Ömer, Kar, G., Mart, M., Tümkaya, Selim   +4 more
core   +1 more source

Editorial: Attention and Methylphenidate [PDF]

Frontiers in Behavioral Neuroscience, 2020
Avi Avital, Iris Manor, David Coghill, David Coghill   +3 more
openaire   +5 more sources

International Swiss Primary Hypersomnolence and Narcolepsy Cohort Study (iSPHYNCS): the impact of psychiatric comorbidities on daily life in central disorders of hypersomnolence—a vicious circle

Journal of Sleep Research, Volume 34, Issue 3, June 2025.
Summary Presence of psychiatric comorbidities is well documented in narcolepsy type‐1 (NT1) but there are limited data on patients with ‘other central disorders of hypersomnolence’ (OCH). This study aimed to investigate frequency of psychiatric comorbidities in patients with NT1 and OCH, and to evaluate their impact on quality of life and sleep as an ...
Merve Aktan Suzgun, Elena S. Wenz, Julia van der Meer, Livia G. Fregolente, Jan D. Warncke, Silvia Miano, Jens Acker, Mathias Strub, Elisabeth Olliges, Ramin Khatami, Markus H. Schmidt, iSPHYNCS Investigators, Claudio L. A. Bassetti, Sigrid von Manitius   +13 more
wiley   +1 more source

Trends and variation in issuance of high‐cost narcolepsy drugs by NHS England organisations and regions from 2019 to 2022

Journal of Sleep Research, EarlyView.
Summary Clinicians and people with narcolepsy report varied access to higher‐cost narcolepsy treatments in England associated with variations in national and local commissioning. There are no publicly available data quantifying use of these drugs to support policy decisions. We therefore aimed to describe national, regional and local prescribing trends
Frederick van Someren, Milan Wiedemann, Charlotte Warren‐Gash, Martina Sykorova, Hema Mistry, Michelle A. Miller, Guy Leschziner, Ellen Nolte, Aurélien Belot, Ian E. Smith, Tim Quinnell, Sofia H. Eriksson, Helen Strongman   +12 more
wiley   +1 more source

Methylphenidate Abuse

Pediatric Neurology Briefs, 1994
The clinical findings associated with IV methylphenidate/pentazocine abuse in emergency department visits are reported from the University of Missouri-Kansas City, MO.
openaire   +3 more sources

MRI‐based surrogates of brain clearance in narcolepsy type 1

Journal of Sleep Research, EarlyView.
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese, Jari K. Gool, Gert Jan Lammers, Ysbrand D. van der Werf, Matthias J. P. van Osch, Rolf Fronczek, Lydiane Hirschler   +6 more
wiley   +1 more source

The striatal dopamine transporter in first-episode, drug-naive schizophrenic patients: evaluation by the new SPECT-ligand[99mTc]TRODAT-1 [PDF]

, 2005
Following the current hypothesis that acute schizophrenic psychotic illness is associated with a triatal ‘hyperdopaminergic state’, presynaptic integrity and dopamine transporter (DAT) density in first-episode, neuroleptic-naive schizophrenic patients ...
Abi-Dargham A, Bannon M J, C. La Fougère, Ciliax B J, Dresel S H, E. M. Meisenzahl, G. J. E Schmitt, H- J. Möller, K. Hahn, Kuikka J T, Mozley P, Mozley P, S. Dresel, T. Frodl   +13 more
core   +1 more source

Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Outpatients With Sleep Problems and Depression, Attention Deficit Disorder, or Bipolar Disorder: A Randomised Controlled Trial

Journal of Sleep Research, EarlyView.
ABSTRACT This study aimed to investigate the efficacy of a Danish adaption of a transdiagnostic sleep and circadian intervention, combining cognitive behavioural therapy for insomnia with chronotherapy. A randomised controlled trial enrolling 88 outpatients with depression, attention deficit disorder, or bipolar disorder suffering from insomnia or ...
Mette Kragh, Henny Dyrberg, Sanne Toft Kristiansen, Maria Speed, Pernille Pedersen, Klaus Martiny   +5 more
wiley   +1 more source

POSTOPERATIVE EFFECTS OF METHYLPHENIDATE

British Journal of Anaesthesia, 1980
A double-blind study is described in which the analgesic and analeptic properties of methylphenidate were investigated in 63 patients following surgery. No effect of methylphenidate on postoperative pain was observed. However, methylphenidate reduced sedation up to 30 min after operation, and improved respiratory function up to 180 min in patients ...
J.M. Fryer, M.E. Dodson
openaire   +3 more sources