Results 81 to 90 of about 526,283 (203)

One year results of intraarticular platelet rich plasma in adhesive capsulitis of shoulder

Journal of Orthopaedic Reports
Introduction: Adhesive capsulitis (AC) is characterized by persistent inflammatory changes of the glenohumeral joint capsule leading to a thick, contracted capsule with a painful significant reduction of active & passive movement.
Sudhir Singh, Prakhar Agarwal, Abhishek Sharma   +2 more
doaj   +1 more source

Comparison of the effects of chronic intraarticular administration of tenoxicam diclofenac and methylprednisolone in healthy rats

Acta Orthopaedica et Traumatologica Turcica, 2020
Objective: Lyophilized drug manufacturing and intra-articular (IA) applications have increased to address gastrointestinal side effects resulting from chronic treatment with non-steroidal anti-inflammatory drugs (NSAIDs) for degenerative joint disease ...
Mehmet Mufit Orak, Dursun Ak, Ahmet Midi, Berna Lacin, Sevim Purisa, Guven Bulut   +5 more
doaj   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

In vitro toxicity of local anaesthetics and corticosteroids on supraspinatus tenocyte viability and metabolism

Journal of Orthopaedic Translation, 2017
Background/Objective: The purpose of this study was to evaluate supraspinatus tenocyte viability and metabolism in explants exposed to various local anaesthetics and corticosteroids.
Clayton W. Nuelle, Cristi R. Cook, Aaron M. Stoker, James L. Cook, Seth L. Sherman   +4 more
doaj   +1 more source

Case Report of IgG4‐Related Autoimmune Pancreatitis

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This case presents a clear diagnosis with a complete chain of clinical evidence. Long‐term follow‐up revealed that, despite excellent disease control, the condition relapsed more than 6 months after discontinuation of glucocorticoids, with a tendency toward further progression.
Rui Yu, Shiyu Zhang, Yanping Zhao, Jingdong Xiao, Chuijie Wang, Yufeng Li, Ziting Mo, Xihan Zhu   +7 more
wiley   +1 more source

Linear Supravenous Hypopigmentation Four Months After Methylprednisolone Tendon Sheath Injection for Tendinitis

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Linear hypopigmentation tracking superficial veins can occur weeks to months after a steroid injection. Recognizing this as a benign, self‐resolving process can prevent misdiagnosis and support conservative management.
Emily Ames, Victor Huang
wiley   +1 more source

Safety Assessment and Pharmacokinetics of Intrathecal Methylprednisolone Acetate in Dogs

, 2012
Background Intrathecal methylprednisolone acetate (MPA) has been used in patients with chronic pain syndromes. Its safety has been debated after reports of adverse events.
Marjorie R. Grafe, Cor J. Kalkman, P. C. Willem Meulenhoff, Albert J. M. van Wijck, Joanne Steinauer, Mienke Rijsdijk, Tony L. Yaksh   +6 more
core   +1 more source

Postoperative Pain Management After Lumbar Discectomy. A Systematic Review With Meta‐Analyses and Trial Sequential Analyses

European Journal of Pain, Volume 30, Issue 4, April 2026.
ABSTRACT Background Inadequate postoperative pain management after lumbar discectomy may delay recovery, increase the risk of chronic pain, and prolong hospitalization. Effective analgesic strategies must balance pain control with minimal adverse effects.
Josephine Zachodnik, Rachid Bech‐Azeddine, Magnus Sandberg, Rebecca Scherwin, Rikke Malene Hartvigsen Grønholm Jepsen, Louise Møller Jørgensen, Kasper Højgaard Thybo, Anja Geisler   +7 more
wiley   +1 more source

A systematic review of glucocorticoid use in type 1 diabetes: Glycaemic effects and clinical management strategies

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2594-2614, April 2026.
Abstract Glucocorticoids (GCs) are widely utilised for the treatment of inflammatory and autoimmune conditions but often precipitate significant hyperglycaemia. People with type 1 diabetes (PWT1D) may be particularly affected due to the challenges of adjusting insulin dosing, for which recommendations remain unclear.
Alexandra Katz, Aidan Shulkin, Asmaa Housni, Amélie Roy‐Fleming, Rémi Rabasa‐Lhoret, Jean‐Francois Yale, Michael A. Tsoukas, Tricia M. Peters, Anne‐Sophie Brazeau   +8 more
wiley   +1 more source

The use of immunomodulatory therapy in pregnant patients with multiple sclerosis

Aktualności Neurologiczne, 2018
Multiple sclerosis is a chronic autoimmune disease which mainly affects young adults – women are 2–3 times more likely to be affected than men. The highest incidence in the procreative age entails the issue of the coexistence of the disease with ...
Julia Rudnicka-Czerwiec, Małgorzata Popiel, Halina Bartosik-Psujek   +2 more
doaj   +1 more source