Results 91 to 100 of about 4,160 (205)

Spinal Cord Stimulation Modulates Supraspinal Centers of the Descending Antinociceptive System in Rats with Unilateral Spinal Nerve Injury

Molecular Pain, 2015
Background The descending antinociceptive system (DAS) is thought to play crucial roles in the antinociceptive effect of spinal cord stimulation (SCS), especially through its serotonergic pathway.
Toshiharu Tazawa, Yoshinori Kamiya, Ayako Kobayashi, Kensuke Saeki, Masahito Takiguchi, Yusuke Nakahashi, Hironobu Shinbori, Kengo Funakoshi, Takahisa Goto   +8 more
doaj   +1 more source

Effectiveness of methysergide in relation to clinical features of migraine

, 1985
Clinical data collected during a comparative trial of serotonin antagonists was reanalysed to determine whether particular migrainous features were associated with a good response to methysergide.
Drummond, P.D.
core  

Some 5-hydroxytryptamine-like actions of fenfluramine: a comparison with (+)-amphetamine and diethylpropion

, 1971
The 5-hydroxytryptamine (5-HT)-like effects of fenfluramine have been investigated in mice in two different experiments. In a behavioural test in mice pretreated with tranylcypromine, fenfluramine caused stereotyped changes which were similar to those ...
A B WILSON, ELIZABETH BOXALL, SUSAN R MAYER, P J SOUTHGATE   +3 more
core   +1 more source

Mode of action of ergonovine on isolated porcine coronary artery: the role of Ca²⁺

, 1983
Coronary vasoconstrictor responses to ergonovine were examined in helical coronary arterial strips of young swine. Both ergonovine and serotonin (5-hydroxytryptamine) produced dose-dependent contractions of the strips.
H. C. Stanton, M. A. Griffin, Lois B. Rosenberger   +2 more
core   +1 more source

PROSTAGLANDINS AND 5-HT RESPONSE ON GASTRIC SECRETION IN ALBINO RATS [PDF]

, 2015
Prostaglandins (PGE1 ) 0.1, 0.2 and 0.4 mg/kg and 5-hydroxytryptamine (5-HT) 1, 2.5 and 5 mg/kg dose dependently inhibited gastric secretion in pyloric legated rats model While PGF2 ∝ 0.1, 0.4 and 1mg/kg inhibited gastric acid secretion. Methysergide
S.K. Bandyopadhyay, P.K. Debnath, T. K. Mandal, Anjan Adhikari, Tapas Sur   +4 more
core   +1 more source

Salt appetite: interaction of forebrain angiotensinergic and hindbrain serotonergic mechanisms

, 1998
Methysergide injected bilaterally into the lateral parabrachial nucleus (LPBN) increases NaCl intake in several models of renin-dependent salt appetite.
Robert L Thunhorst, Jose Vanderlei Menani, Colombari, DSA, Johnson, A. K., Debora S.A Colombari, Terry G Beltz, Beltz, T. G., Thunhorst, R. L., Alan Kim Johnson, Menani, José Vanderlei [UNESP], Menani, José Vanderlei   +10 more
core   +1 more source

Serotonergic receptor blockade in the lateral parabrachial nucleus: Different effects on hypertonic and isotonic NaCl intake

, 2008
Hypertonic NaCl intake is produced by serotonin receptor antagonism in the lateral parabrachial nucleus (LPBN) of dehydrated rats or in rats pretreated with a mineralocorticoid, for example deoxycorticosterone (DOCA), that receive an ...
De Luca, Laurival A. [UNESP], David, Richard B. [UNESP], De Luca, Laurival A., David, Richard B., Menani, José Vanderlei [UNESP], Menani, José Vanderlei   +5 more
core   +1 more source

THE EFFECTS OF PROSTAGLANDINS E1, E2 AND F2α ON THE CUTANEOUS VASCULATURE OF THE RAT

, 1976
The responses of the rat cutaneous vasculature to prostaglandins E, E and F have been investigated by a photomicrographic technique. Prostaglandin E produced transient arterial constriction which was blocked by local pretreatment of preparations with ...
CHAHL L.A., LADD R.J.
core   +1 more source

Antagonism of 5-hydroxytryptamine-induced bronchospasm in guinea-pigs by 8β-carbobenzyloxy-aminomethyl-1-methyl-10α-ergoline

, 1965
The drug 8β-carbobenzyloxyaminomethyl-1-methyl-10α-ergoline (mce) has been shown to have a potent and prolonged antagonism to 5-hydroxytryptamine-induced bronchospasm in guinea-pigs. 4–5 hr after 2 μg/kg of mce, given intraveneously, the effects of the 5-
C Beretta, A H Glässer, M B Nobili, R SILVESTRI   +3 more
core   +1 more source

Simulation of acute myopericarditis by constrictive pericardial disease with endomyocardial fibrosis due to methysergide therapy

, 2010
Methysergide (Sansert) has been associated with numerous fibrotic disorders. In particular, multiple cardiac lesions have been described in cases where methysergide was thought to have played a causative role.
Myron C. Gerson, John B. O'Connell, A. Daniel Harbin   +2 more
core   +1 more source