Results 81 to 90 of about 4,160 (205)
Orphanet Journal of Rare Diseases, 2008 Cluster headache (CH) is a primary headache disease characterized by recurrent short-lasting attacks (15 to 180 minutes) of excruciating unilateral periorbital pain accompanied by ipsilateral autonomic signs (lacrimation, nasal congestion, ptosis, miosis,
Ducros Anne, Leroux Elizabeth
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Molecular Pain, 2011 Background The role of serotonin (5-hydroxytrptamine, 5-HT) in the modulation of pain has been widely studied. Previous work led to the hypothesis that 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, might by itself influence pain ...
Moessner Rainald +5 more
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Effect of methysergide pretreatment on thrombin-induced pulmonary oedema in the rat
, 1984 Microembolic pulmonary oedema was induced by injection of thrombin (500 NIH units/kg body weight) i.v. in rats in which fibrinolysis had been inhibited by pretreatment with trans-4-aminomethyl-cyclohexanoid-carboxylic acid (AMCA). To evaluate the role of
Sandler, H, Gerdin, Bengt,
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A dual action of 5-hydroxytryptamine on the ovarian suspensory ligament of the rat
, 1976 5-Hydroxytryptamine has a dual effect on the spontaneously contracting rat ovarian ligament, in vitro, a contraction which is antagonized by the prior administration of methysergide and a relaxation of the ligament observed in the methysergide-treated ...
W G Davis
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Anomalous responses to histamine stimulation of guinea-pig oesophageal muscularis mucosae
, 1991 The incomplete tachyphylaxis of the contractile response to the H-1-stimulants observed on guinea-pig oesophageal muscularis mucosae seems to be H-2- and H-3-antagonist as well as atropine- and tetrodotoxin-resistant.
T. Vitali +6 more
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The pharmacological profile of ovalbumin-induced paw oedema in rats
Mediators of Inflammation, 2002 Rats are commonly used in anaphylaxis models, mainly in intestinal anaphylaxis. Hypersensitivity mechanisms are complex and they are not clearly defined. Ovalbumin (OVA) is commonly used for studies on the hypersensitivity mechanism.
R. F. G. Feitosa +5 more
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, 1995 Despite extensive study of the effects of various pharmacological agents on the thyrotropin (TSH) and prolactin (PRL) responses to TRH challenge, the effect of serotoninergic agents remains inconclusive. We studied the effect of the serotonin antagonists
PAPAKOSTAS, YG +4 more
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Effect of 5-HT on Trica5-HT1 in presence of different concentrations of antagonist.
, 2013 Dose-dependent activation of Trica5-HT1 was measured in CHO-WTA11 cells with 1 nM –1 mM 5-HT in presence of 10 nM –1 mM antagonist: (A) prazosin, (B) methysergide and (C) methiothepin.
Heleen Verlinden (104923) +4 more
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Journal of Venomous Animals and Toxins including Tropical Diseases, 2017 Background Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives.
Renata Gonçalves Dias +7 more
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, 1995 The effect of nicotine on endogenous basal GABA outflow was studied in guinea‐pig cerebral cortex slices. Nicotine 1.86‐18.6 μmol 1−1 significantly decreased the basal, tetrodotoxin‐sensitive GABA efflux, whereas at higher concentrations (186–620 μmol 1 ...
Luca Ferraro +13 more
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