Results 61 to 70 of about 4,160 (205)

Effect of serotonin (5-HT), 5-MeOT, 5-CT, R(+)-lisuride and methysergide on the transepithelial potential (TEP) of blowfly salivary glands.

, 2012
Application of 30 nM 5-HT resulted in a biphasic change of the TEP, a negative phase during exposure to 5-HT and a positive phase after washout of 5-HT.
Sabine Balfanz (120824), Nadine Jordan (120821), Bernd Walz (48845), Claudia Röser (120818), Wolfgang Blenau (120829), Otto Baumann (48844), Arnd Baumann (120826)   +6 more
core   +1 more source

Inaugural Review Prize 2023: The exercise hyperpnoea dilemma: A 21st‐century perspective

Experimental Physiology, Volume 109, Issue 8, Page 1217-1237, 1 August 2024.
Abstract During mild or moderate exercise, alveolar ventilation increases in direct proportion to metabolic rate, regulating arterial CO2 pressure near resting levels. Mechanisms giving rise to the hyperpnoea of exercise are unsettled despite over a century of investigation.
Joseph F. Welch, Gordon S. Mitchell
wiley   +1 more source

A pre-junctional action of 5-hydroxytryptamine and methysergide on noradrenergic nerves in dog isolated saphenous vein

, 1981
Electrical stimulation (2 Hz for 2 min) of dog isolated saphenous vein strips pre-incubated with tritiated noradrenaline increased the overflow of tritium of which about 80% was noradrenaline. 5-Hydroxytryptamine (5-HT; 1·0 × 10−9-1·0 × 10−7 mol litre−1)
W FENIUK, A D WATTS, P P A HUMPHREY
core   +1 more source

Excitatory action of low frequency depolarizing GABA/glycine synaptic inputs is prevalent in prenatal spinal SOD1G93A motoneurons

The Journal of Physiology, Volume 602, Issue 5, Page 913-932, 1 March 2024.
Abstract figure legend Left: the firing of wild‐type (WT) prenatal (embyronic day 17.5) lumbar spinal motoneurons (MNs) exhibiting a low input resistance (<100 MΩ) is inhibited by low frequency depolarizing GABAergic/glycinergic postsynaptic potentials (dGPSPs). Red dots indicate GABA/glycine terminals on the MN soma and proximal dendrites.
Hongmei Zhu, Urvashi Dalvi, William Cazenave, Daniel Cattaert, Pascal Branchereau   +4 more
wiley   +1 more source

Cluster Headache and Its Cousins: A Family of Pain Management Problems

Pain Research and Management, 2000
Cluster headache causes great misery because of the severity, frequency and repetitiveness of its attacks, and the fear (justified in a few sufferers) that the attacks will respond to nothing and will never cease.
John Edmeads
doaj   +1 more source

Valvular Heart Disease Associated with Long-term Treatment by Methysergide: a Case Report

, 2014
This case report concerns a woman treated continuously since at least 10 years by methysergide for cluster headache. The echocardiographic and histological features of the severe valve fibrosis presented by this patient are very ...
Jean-Paul Rémadi, Sylvestre Maréchaux, Elise Arnalsteen, Valérie Gras, Michel Andréjak, Catherine Szymanski, Christophe Tribouilloy   +6 more
core   +1 more source

Transition‐Metal‐Free Synthesis of 2‐Substituted Benzo[cd]Indoles via the Reaction of 1‐Halo‐8‐lithionaphthalenes with Nitriles

Chemistry – A European Journal, Volume 30, Issue 10, February 16, 2024.
A simple and effective organolithium approach to the synthesis of 2‐substituted benzo[cd]indoles from peri‐dihalonaphthalenes and nitriles has been developed. The reaction proceeds via a surprisingly easy intramolecular aromatic nucleophilic substitution facilitated by the “clothespin effect”.
Semyon V. Tsybulin, Mark V. Kaplanskiy, Alexander S. Antonov   +2 more
wiley   +1 more source

Pre-injury administration of morphine prevents development of neuropathic hyperalgesia through activation of descending monoaminergic mechanisms in the spinal cord in mice

Molecular Pain, 2005
The present study examined whether pre-injury administration of morphine can prevent partial sciatic nerve injury-induced neuropathic pain in mice. We observed that pre-injury administration of subcutaneous (s.c.) and intracerebroventricular (i.c.v ...
Rashid Md Harunor, Ueda Hiroshi
doaj   +1 more source

Sodium intake, brain c-Fos protein and gastric emptying in cell-dehydrated rats treated with methysergide into the lateral parabrachial nucleus

, 2015
Previous studies from our laboratory have shown that methysergide, a serotonergic antagonist, injected into the lateral parabrachial nucleus (LPBN) combined with a pre-load of 2 M NaCl, given by gavage, induces 0.3 M NaCl intake.
Luca, Laurival A. de, David, Richard B., Vendramini, Regina C. [UNESP], Menani, José V. [UNESP], Vendramini, Regina C., Antunes-Rodrigues, José, Roncari, Camila F., Lauar, Mariana R., Luca, Laurival A. de [UNESP], David, Richard B. [UNESP], Lauar, Mariana R. [UNESP], Roncari, Camila F. [UNESP], Menani, José V.   +12 more
core   +1 more source

Risks for animal health related to the presence of ergot alkaloids in feed

EFSA Journal, Volume 22, Issue 1, January 2024.
Abstract The European Commission requested EFSA to provide an update of the 2012 Scientific Opinion of the Panel on Contaminants in the Food Chain (CONTAM) on the risks for animal health related to the presence of ergot alkaloids (EAs) in feed. EAs are produced by several fungi of the Claviceps and Epichloë genera.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jürgen Gropp, Patrick Mulder, Isabelle P. Oswald, Ruud Woutersen, Jose Ángel Gómez Ruiz, Elena Rovesti, Laurentius (Ron) Hoogenboom   +23 more
wiley   +1 more source