Results 41 to 50 of about 5,127 (197)

New Approaches to Shifting the Migraine Treatment Paradigm

Frontiers in Pain Research, 2022
The standard of care paradigm for migraine treatment has been based almost exclusively on approaches that grew out of the happenstance use of market pharmaceuticals.
Brian Johnson, Frederick G. Freitag
doaj   +1 more source

(+/-)-Gelliusines A and B, two diastereomeric brominated tris-indole alkaloids from a deep water New Caledonian marine sponge (Gellius or Orina sp.) [PDF]

, 1994
Two new diastereomeric brominated tris-indole alkaloids occurring as enantiomeric pairs, (±)-gelliusine A (I) and its isomer (±)-gelliusine B, have been isolated from a deep water New Caledonian sponge (Gellius or Orina sp.), whose crude ext.
Bifulco, G., Bruno, I., Calignano, A., Debitus, Cécile, Minale, L., Riccio, R.   +5 more
core   +1 more source

Heterosynaptic long-term potentiation from the anterior cingulate cortex to spinal cord in adult rats

Molecular Pain, 2018
Spinal nociceptive transmission receives biphasic modulation from supraspinal structures. Recent studies demonstrate that the anterior cingulate cortex facilitates spinal excitatory synaptic transmission and nociceptive reflex.
Qi-Yu Chen, Tao Chen, Li-Jun Zhou, Xian-Guo Liu, Min Zhuo   +4 more
doaj   +1 more source

Neurotransmitter Mechanisms of Ketamine and Ketamine–Magnesium Sulfate-Induced Hypothermia: Evidence for Serotonergic and Adrenergic Involvement Without GABA_A Contributions

Brain Sciences
Background: Ketamine and magnesium sulfate are commonly used perioperatively to prevent shivering, a frequent and clinically relevant complication of spinal and general anesthesia.
Katarina Savić Vujović, Sonja Vučković, Lara Samardžić, Branislava Medić, Dragana Srebro, Ana Jotić, Ivana Ćirković   +6 more
doaj   +1 more source

Neurogenic mediators contribute to local edema induced by Micrurus lemniscatus venom. [PDF]

PLoS Neglected Tropical Diseases, 2017
Micrurus is one of the four snake genera of medical importance in Brazil. Coral snakes have a broad geographic distribution from the southern United States to Argentina.
Luciana Lyra Casais-E-Silva, Catarina Teixeira   +1 more
doaj   +1 more source

Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]

, 2004
Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C., Laakmann, G., Schule, C.   +2 more
core   +1 more source

POSSIBLE RETROPERITONEAL FIBROSIS AND METHYSERGIDE [PDF]

Lancet, The, 1965
exaly   +4 more sources

Antinociceptive Effect of Shakuyakukanzoto, a Kampo Medicine, in Diabetic Mice

Journal of Pharmacological Sciences, 2005
In this study, the antinociceptive effect of shakuyakukanzoto was investigated using streptozotocin-induced diabetic mice to certify its analgesic effect on diabetic patients.
Yuji Omiya, Yasuyuki Suzuki, Mitsutoshi Yuzurihara, Mikio Murata, Masaki Aburada, Yoshio Kase, Shuichi Takeda   +6 more
doaj   +1 more source

Migraine: Diagnosis, treatment and understanding c1960-2010 [PDF]

, 2014
seminar transcriptThere are around eight million migraine sufferers in the UK today. This Witness Seminar looked at the last 50 years of research into the diagnosis and treatment of the condition and the changing attitudes of the medical profession ...
Overy, C, Tansey, EM
core  

Melatonin attenuates oxidative stress and modulates inflammatory response after experimental burn trauma [PDF]

, 2018
Introduction. Thermal injury activates an inflammatory response. Melatonin possesses anti-oxidant and anti-inflammatory properties. The objective of the present work was to study melatonin effects on the inflammatory response under ...
Atanasova, Milena, Bekyarova, Ganka, Hristova, Minka, Tzaneva, Maria   +3 more
core   +3 more sources