Results 21 to 30 of about 5,127 (197)

The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small Intestine [PDF]

, 2014
Background: The main source of 5-HT in body is in enterchromafin cells of intestine, different studies mentioned different roles for endogenous 5-HT and receptors involved and it is not clearified the mechanism of action of endogenous 5-HT. Objectives:
Bianchi C, Broad RM, Buchheit KH, Budhoo MR, Carter D, Costall B, Costa M, Craig DA, D'Amato M, Eglen RM, Engel G, Erspamer V, Feldberg W, Gale JD, Gebauer A, Gershon MD, Gozlan H, Hedge SS, Hume SP, Humphrey PP, Ivancheva C, Javid FA, Kilbinger H, Kuemmerle JF, Leysen JE, Malleron JL, Mawe GM, Nowak TV, Pan H, Racke K, Radomirov R, Satoh Y, Weber LJ, Yamamoto I   +33 more
core   +1 more source

Long‐term efficacy and safety of erenumab in patients with chronic migraine in whom prior preventive treatments had failed: A subgroup analysis

Headache: The Journal of Head and Face Pain, Volume 62, Issue 5, Page 624-633, May 2022., 2022
Abstract Objective To assess the long‐term efficacy and safety of erenumab in the subgroup of patients with chronic migraine (CM) in whom prior preventive treatments had failed (TF) (≥1, ≥2, and ≥3 TF medication categories) and never failed (preventive naïve or prior preventive treatments had not failed), using the data from a 52‐week, open‐label ...
Messoud Ashina, Stewart J. Tepper, Jan Lewis Brandes, Uwe Reuter, Guy P. Boudreau, Mark Weatherall, Andreas R. Gantenbein, David Doležil, Jan Klatt, Andrea Wang, Ananda Krishna Karanam, Sunfa Cheng, Daniel D. Mikol   +12 more
wiley   +1 more source

Idiopathic red ear syndrome: A rare case report

Clinical Case Reports, Volume 10, Issue 3, March 2022., 2022
Abstract Red ear syndrome (RES) is a very rare disorder that is characterized by a unilateral or bilateral attack of paroxysmal burning sensation and reddening of the external ear. The duration of symptoms ranges from a few seconds to hours. It can occur spontaneously or be triggered by rubbing of the ear, heat or cold stimulation, brushing of hair ...
Brihaspati Sigdel, Amrit Pokhrel
wiley   +1 more source

Cluster headache epidemiology including pediatric onset, sex, and ICHD criteria: Results from the International Cluster Headache Questionnaire

Headache: The Journal of Head and Face Pain, Volume 61, Issue 10, Page 1511-1520, November / December 2021., 2021
Abstract Objective To validate the diagnoses and to investigate epidemiological data from an international, non‐clinic‐based, and large (n = 1604) survey of participants with cluster headache. Background There are several limitations in current epidemiological data in cluster headache including a lack of large non‐clinic‐based studies.
Larry I. Schor, Stuart M. Pearson, Robert E. Shapiro, Wei Zhang, Hongyu Miao, Mark J. Burish   +5 more
wiley   +1 more source

Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]

, 2013
Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
core   +1 more source

Changes in use of acute and preventive medications for migraine after erenumab initiation over 12 months: A United States retrospective cohort study. [PDF]

Headache
Abstract Objective To assess changes in real‐world use of acute and preventive medications for migraine over a 12‐month follow‐up period in the United States following initiation of the anti‐calcitonin gene‐related peptide (CGRP) pathway monoclonal antibody (mAb) erenumab.
Multani JK, Urman R, Park AS, Gill K, Vuvu F, Sun K, Patel LB, Stockl KM, Hawkins K, Rhyne C, Bensink ME.   +10 more
europepmc   +2 more sources

Serotonin increases cilia-driven particle transport via an acetylcholine-independent pathway in the mouse trachea. [PDF]

PLoS ONE, 2009
BACKGROUND: Mucociliary clearance in the airways is driven by the coordinated beating of ciliated cells. Classical neuromediators such as noradrenalin and acetylcholine increase ciliary beat frequency and thus cilia-driven transport.
Peter König, Benjamin Krain, Gabriela Krasteva, Wolfgang Kummer   +3 more
doaj   +1 more source

Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats

Molecular Pain, 2010
Background Descending pronociceptive pathways may be implicated in states of persistent pain. Paw skin incision is a well-established postoperative pain model that causes behavioral nociceptive responses and enhanced excitability of spinal dorsal horn ...
Prado Wiliam A, Del Bel Elaine A, Dias Quintino M, Silveira João   +3 more
doaj   +1 more source

The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]

, 1964
1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
core   +1 more source

The Tricyclic Antidepressant Clomipramine Increases Plasma Glucose Levels of Mice

Journal of Pharmacological Sciences, 2003
: Effects of the tricyclic antidepressant clomipramine on plasma glucose levels in mice were studied. Clomipramine at doses ranging 5 – 20 mg/kg elicited significant hyperglycemia in mice.
Yumi Sugimoto, Kiyo Inoue, Jun Yamada
doaj   +1 more source