Results 31 to 40 of about 5,127 (197)

PROSTAGLANDINS AND 5-HT RESPONSE ON GASTRIC SECRETION IN ALBINO RATS [PDF]

open access: yesExploratory Animal and Medical Research, 2015
Prostaglandins (PGE1 ) 0.1, 0.2 and 0.4 mg/kg and 5-hydroxytryptamine (5-HT) 1, 2.5 and 5 mg/kg dose dependently inhibited gastric secretion in pyloric legated rats model While PGF2 ∝ 0.1, 0.4 and 1mg/kg inhibited gastric acid secretion. Methysergide
P.K. Debnath   +4 more
doaj  

Long-Lasting and Additive Analgesic Effects of Combined Treatment of Bee Venom Acupuncture and Venlafaxine on Paclitaxel-Induced Allodynia in Mice

open access: yesToxins, 2020
Paclitaxel, a primary chemotherapeutic agent used to treat numerous solid malignancies, is commonly associated with debilitating peripheral neuropathy. However, a satisfactory gold-standard monotherapy for this neuropathic pain is not currently available.
Daxian Li, Ju Hyuk Yoo, Sun Kwang Kim
doaj   +1 more source

Characterization of a new type of neuronal 5-HT G- protein coupled receptor in the cestode nervous system.

open access: yesPLoS ONE, 2021
Cestodes are platyhelminth parasites with a wide range of hosts that cause neglected diseases. Neurotransmitter signaling is of critical importance for these parasites which lack circulatory, respiratory and digestive systems.
Federico Camicia   +9 more
doaj   +2 more sources

Antinociceptive effect of chrysin in diabetic neuropathy and formalin-induced pain models

open access: yesAnimal Cells and Systems, 2020
Chrysin, a natural flavonoid, is the main ingredient of many medicinal plants, which shows potent pharmacological properties. In the present study, the antinociceptive effects of chrysin were examined in ICR mice. Chrysin orally administered at the doses
Jae-Seung Hong   +6 more
doaj   +1 more source

Latent inhibition in an insect: the role of aminergic signaling [PDF]

open access: yes, 2012
Latent inhibition (LI) is a decrement in learning performance that results from the nonreinforced pre-exposure of the to-beconditioned stimulus, in both vertebrates and invertebrates.
Devaud, Jean Marc   +3 more
core   +2 more sources

Involvement of serotonin and eicosanoids in the rat paw oedema response to the essential oil of Pilocarpus spicatus

open access: yesMediators of Inflammation, 1992
Subplantar injection of Pilocarpus spicatus essential oil (PSEO), induced rat hindpaw oedema in a dose-dependent manner. The time course study revealed that when compared to carrageenan-induced oedema, the oedema response to PSEO was greater at 1 h post ...
J. C. R. Silva, V. S. N. Rao
doaj   +1 more source

Mechanisms of Analgesic Action of Neurotropin on Chronic Pain in Adjuvant-Induced Arthritic Rat: Roles of Descending Noradrenergic and Serotonergic Systems

open access: yesJournal of Pharmacological Sciences, 2005
Neurotropin®, a non-protein extract from the inflamed skin of rabbits inoculated with vaccinia virus, has been clinically used as an analgesic drug for treatment of chronic pain.
Tomoshi Miura   +5 more
doaj   +1 more source

Effect of peripheral 5-HT on glucose and lipid metabolism in wether sheep. [PDF]

open access: yesPLoS ONE, 2014
In mice, peripheral 5-HT induces an increase in the plasma concentrations of glucose, insulin and bile acids, and a decrease in plasma triglyceride, NEFA and cholesterol concentrations.
Hitoshi Watanabe   +17 more
doaj   +1 more source

Pharmacological Characterization of Itch-Associated Response Induced by Repeated Application of Oxazolone in Mice

open access: yesJournal of Pharmacological Sciences, 2010
We investigated pharmacological characteristics of the itch-associated response to chronic dermatitis induced by 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one (oxazolone) repeated application in mice.
Yukihito Tsukumo   +2 more
doaj   +1 more source

Inhibition Mechanism of Gosha-jinki-gan on the Micturition Reflex in Rats

open access: yesJournal of Pharmacological Sciences, 2004
We investigated the actions of Gosha-jinki-gan, a traditional Japanese medicine containing processed Aconiti tubers, on urinary bladder function in anesthetized rats.
Akinobu Gotoh   +8 more
doaj   +1 more source

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