Results 11 to 20 of about 5,127 (197)
Tumor necrosis factor alpha induces a serotonin dependent early increase in ciliary beat frequency and epithelial transport velocity in murine tracheae. [PDF]
PLoS ONE, 2014 The tracheal epithelium prevents via its highly effective clearance mechanism the contamination of the lower airways by pathogens. This mechanism is driven by ciliary bearing cells which are not only in contact with the gas phase; in addition they are ...
Sebastian Weiterer +6 more
doaj +5 more sources
Efficacy and tolerability of intravenous methylergonovine in migraine female patients attending the emergency department: a pilot open-label study [PDF]
Head & Face Medicine, 2009 Background Methylergonovine is an ergot alkaloid widely used in postpartum women. It is also an active metabolite of methysergide and previous studies suggest that it could be effective against refractory headache and cluster headache. The purpose of the
Rico-Villademoros Fernando +4 more
doaj +3 more sources
Dihydroergotamine, ergotamine, methysergide and sumatriptan - Basic science in relation to migraine treatment [PDF]
, 2012 The 5-hydroxytryptamine (5-HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5-HT 1B, 5-HT1D, and 5-HT1F receptors.
Dahlöf, C. (Carl) +1 more
core +24 more sources
The clinical effect of an implanted vagus nerve stimulator in a patient with chronic cluster headache and focal epilepsy - A case report. [PDF]
HeadacheAbstract Background Treatment for chronic cluster headache (CCH) is often insufficient. Non‐invasive vagus nerve stimulation (nVNS) was shown to be effective as acute treatment in episodic cluster headache (ECH) and open‐label studies have shown a potential effect in CCH.
van Tilborg PJ +3 more
europepmc +2 more sources
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
British Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +165 more
wiley +1 more source
5‐HT7 receptors mediate dilation of rat cremaster muscle arterioles in vivo
Microcirculation, Volume 30, Issue 5-6, August 2023., 2023 Abstract Objective Serotonin (5‐HT) infusion in vivo causes hypotension and a fall in total peripheral resistance. However, the vascular segment and the receptors that mediate this response remain in question. We hypothesized that 5‐HT7 receptors mediate arteriolar dilation to 5‐HT in skeletal muscle microcirculation.
William F. Jackson +4 more
wiley +1 more source
Are psychedelics the answer to chronic pain: A review of current literature
Pain Practice, Volume 23, Issue 4, Page 447-458, April 2023., 2023 Abstract Aims We aim to provide an evidence‐based overview of the use of psychedelics in chronic pain, specifically LSD and psilocybin. Content Chronic pain is a common and complex problem, with an unknown etiology. Psychedelics like lysergic acid diethylamide (LSD) and psilocybin, may play a role in the management of chronic pain.
Nina I. Kooijman +6 more
wiley +1 more source
Clinical Case Reports, Volume 10, Issue 10, October 2022., 2022 Persistent headaches sometimes concern incidental findings: A rare case of internal jugular vein agenesis. Abstract Absence of an internal jugular vein at birth is infrequent. These developmental anomalies affect approximately 0.05 percent to 0.25 percent of the population in the general community.
Mohammad Ashraful Amin +2 more
wiley +1 more source
Generalized morphea following the COVID vaccine: A series of two patients and a bibliographic review
Dermatologic Therapy, Volume 35, Issue 9, September 2022., 2022 Abstract The appearance of morphea after vaccination has been reported to date as single and deep lesions that appear exactly at the site of the skin puncture. It was therefore postulated that the origin could be the trauma related to the injection. The aim of this article is to review the various hypotheses offered in the published literature about ...
Javier Antoñanzas +5 more
wiley +1 more source
United European Gastroenterology Journal, Volume 10, Issue 5, Page 451-464, June 2022., 2022 Abstract Drug‐induced mucosal injury (DIMI) in the gastrointestinal tract is important to recognise, partly because cessation of the culprit agent alone may result in resolution of symptoms. An ever‐growing list of medications, including newer immunotherapeutic agents and targeted therapies, can cause gastrointestinal inflammation of varying severity ...
Naoimh Herlihy, Roger Feakins
wiley +1 more source