Results 101 to 110 of about 58,830 (269)

Comparing the Molecular Pharmacological Properties of Existing β‐Blockers to Determine the Theoretically Most “Ideal” Anti‐Cancer β‐Blocker

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT There is increasing evidence, from cellular, animal and human epidemiological studies, linking β‐blockers with reductions in cancer growth and metastasis. Propranolol is the most investigated β‐blocker for cancer; although as many different off‐patent β‐blockers exist, there is little commercial incentive to drive comparative clinical trials ...
Jillian G. Baker
wiley   +1 more source

Esmolol Endovenoso em Regime Bail Out Para Controlo de Frequência Cardíaca na Tomografia Computorizada Cardíaca [PDF]

, 2016
OBJECTIVE: To evaluate the efficacy and safety of a heart rate (HR) reduction protocol using intravenous esmolol as bailout for failed oral metoprolol regimens in patients undergoing coronary computed tomography angiography (CCTA) with 64-slice ...
Casado, H, Cruz Ferreira, R, Figueiredo, L, Leal, C, Marques, H, Ramos, R, Rosa, S, Santos, R, Saraiva, M   +8 more
core   +1 more source

Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy. [PDF]

, 2019
Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of β1 adrenergic receptors (βARs) on cardiac myocytes.
Irannejad, Roshanak, Nash, Craig A, Smrcka, Alan V, Wei, Wenhui   +3 more
core   +1 more source

Controlled release floating multiparticulates of metoprolol succinate by hot melt extrusion [PDF]

, 2015
YesWe present hot melt extrusion (HME) for the design of floating multiparticulates. Metoprolol succinate was selected as the model drug. Our foremost objective was to optimize the components Eudragit® RS PO, polyethylene oxide (PEO) and hydroxypropyl ...
Devarajan, P.V., Malode, V.N., Paradkar, Anant R.   +2 more
core   +1 more source

Pregnancy and Delivery Outcomes in Vascular Ehlers–Danlos Syndrome: A Retrospective Multicentre Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 3, Page 463-470, February 2026.
ABSTRACT Objective We aim to increase knowledge on pregnancy and delivery risks in vascular Ehlers–Danlos Syndrome (vEDS). Our outcomes can contribute to establishing future guidelines for pregnancy and delivery management in women with vEDS. Design Retrospective multicentre cohort study.
Lisa M. van den Bersselaar, Ingrid M. B. H. van de Laar, Marieke J. H. Baars, Annette Baas, Eelco Dulfer, Apollonia T. J. M. Helderman‐van den Enden, Yvonne Hilhorst‐Hofstee, Robert M. Kauling, Marlies J. E. Kempers, Martijn A. Oudijk, Alessandra Maugeri, Hennie T. Brüggenwirth, Arjan C. Houweling, Serwet Demirdas   +13 more
wiley   +1 more source

Graphene Oxide/Polyethylene Glycol-Stick for Thin Film Microextraction of β-Blockers from Human Oral Fluid by Liquid Chromatography-Tandem Mass Spectrometry

Molecules, 2019
A wooden stick coated with a novel graphene-based nanocomposite (Graphene oxide/polyethylene glycol (GO/PEG)) is introduced and investigated for its efficacy in solid phase microextraction techniques.
Hanieh Karimiyan, Mohammad Reza Hadjmohammadi, Karthik Laxman Kunjali, Mohammad Mahdi Moein, Joydeep Dutta, Mohamed Abdel-Rehim   +5 more
doaj   +1 more source

Coronary collateral perfusion in patients with coronary artery disease: effect of metoprolol [PDF]

, 2017
Background The use of ultrathin Doppler angioplasty guidewires has made it possible to measure collateral flow quantitatively. Pharmacologic interventions have been shown to influence collateral flow and, thus, to affect myocardial ischaemia.
Billinger, Michael, Hess, Otto M., Meier, Bernhard, Raeber, Lorenz, Seiler, Christian, Windecker, Stephan   +5 more
core  

Executive Summary of the 2024 Philippine Clinical Practice Guidelines on the Diagnosis and Management of Acute Severe Blood Pressure Elevation

The Journal of Clinical Hypertension, Volume 28, Issue 2, February 2026.
ABSTRACT A recent survey in the Philippines, PRESYON‐4, showed increasing prevalence of hypertension from 22% in the 1990s to 37% in 2021, of which only 52% were aware of their diagnosis. While rates of treatment and adherence were 68% and 86%, respectively, the rate of BP control was low at 37%. Furthermore, there remained a high degree of unawareness
Deborah Ignacia D. Ona, Felix Eduardo Punzalan, Raymond V. Oliva, Ma. Sergia Fatima Sucaldito, Noel Espallardo, Richard Santos, Hannah Almenario, Karl Murillo, Valentin Dones III, Elmer Jasper Llanes, Lourdes Ella Santos, Maria Cristina San Jose, Alyssa Samantha Fusingan‐Peralta, Rommel Bataclan, Maria Katrina Mata, Pauline Convocar, Aurelia Leus, Gilbert Vilela   +17 more
wiley   +1 more source

Effect of Antihypertensive Treatment on Hypotension, Mortality and Length of Stay in Orthopedic Trauma and First Detected High Blood Pressure Adults in a Large Urban Hospital: A Retrospective Cohort Study

The Journal of Clinical Hypertension, Volume 28, Issue 2, February 2026.
ABSTRACT Trauma is a frequent cause of hospital admission in adults, and while arterial hypertension is common in the general population, reactive hypertension associated with trauma remains poorly studied from a therapeutic perspective. This retrospective cohort study aimed to estimate the impact of antihypertensive treatment on hypotension occurrence,
Carlos José Atencia, Fabian Jaimes
wiley   +1 more source

Evaluation the Metoprolol Effects in Controlled Hypotension and Reduction of Bleeding During Head and Neck Surgery [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2008
Background and objectivesIntraoperative bleeding, which reduces visibility in the operative field, is one of the major problems of head and neck surgeries.
P. Rahimzadeh, S.H.R. Faiz, S.H. Etemadi
doaj   +2 more sources