Results 21 to 30 of about 70,021 (330)
Quercetin declines plasma exposure of metoprolol tartrate in the rat model
Journal of Advanced Pharmaceutical Technology & Research, 2014 The study was undertaken to evaluate the effect of quercetin on the pharmacokinetics of Metoprolol tartrate. A single dose in vivo pharmacokinetic study was carried out in rat models.
Siva R Challa +2 more
doaj +1 more source
Metoprolol blunts the time-dependent progression of infarct size
Basic Research in Cardiology, 2020 Early metoprolol administration protects against myocardial ischemia–reperfusion injury, but its effect on infarct size progression (ischemic injury) is unknown. Eight groups of pigs (total n = 122) underwent coronary artery occlusion of varying duration
M. Lobo-González +12 more
semanticscholar +1 more source
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
, 2012 Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
European Heart Journal, 2016 Aims Contemporary adjuvant treatment for early breast cancer is associated with improved survival but at the cost of increased risk of cardiotoxicity and cardiac dysfunction. We tested the hypothesis that concomitant therapy with the angiotensin receptor
G. Gulati +14 more
semanticscholar +1 more source
Effect on Mortality of Higher Versus Lower β-Blocker (Metoprolol Succinate or Carvedilol) Dose in Patients With Heart Failure [PDF]
, 2018 This study aimed to compare the effect of β-blocker dose and heart rate (HR) on mortality in patients with heart failure with reduced ejection fraction (HFrEF).
Ajam, Samer +4 more
core +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Clinical and clinicoeconomical studies review is presented as well as results of author’s comparative cost analysis on metoprolol tartrate (Betaloc) and metoprolol succinate (Betaloc ZOK) usage in patients with ischemic heart disease.
M. V. Soura
doaj +1 more source
Wurster fluidised bed coating of microparticles: Towards scalable production of oral sustained-release liquid medicines for patients with swallowing difficulties [PDF]
, 2019 © 2019 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium ...
Craig Richardson +5 more
core +1 more source
Cardiovascular Diabetology, 2011 Background Carvedilol has been shown to be superior to metoprolol tartrate to improve clinical outcomes in patients with heart failure (HF), yet the mechanisms responsible for these differences remain unclear.
Køber Lars +8 more
doaj +1 more source
Cardioprotection by early metoprolol- attenuation of ischemic vs. reperfusion injury?
Basic Research in Cardiology, 2020 There is still a need for adjunct cardioprotection on top of timely reperfusion since mortality and morbidity, notably from heart failure, in patients with acute myocardial infarction remain high [11, 12].
P. Kleinbongard
semanticscholar +1 more source
Functional selectivity of GPCR-directed drug action through location bias. [PDF]
, 2017 G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco +6 more
core +3 more sources