Results 41 to 50 of about 31,613 (220)

Experimental methods in chemical engineering: Magnetometry

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Magnetometry is a non‐invasive technique to characterize the behaviour of magnetic materials of which the most common contain Fe, Co, and Ni. Vibrating sample magnetometers (VSMs) vibrate samples at a fixed frequency in a static, homogeneous magnetic field to induce a voltage in pick up coils according to Faraday's law of induction.
Michael Claeys, Dominic De Oliveira, Gregory S. Patience, M. Olga Guerrero‐Pérez   +3 more
wiley   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

Drug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis, Helen G. Gika, Georgios Panagiotoglou, Eleni Parlapani, Pavlos Pavlidis, Nikolaos Raikos   +5 more
wiley   +1 more source

Neutrophil stunning by metoprolol reduces infarct size

, 2017
The β1-adrenergic-receptor (ADRB1) antagonist metoprolol reduces infarct size in acute myocardial infarction (AMI) patients. The prevailing view has been that metoprolol acts mainly on cardiomyocytes.
Garcia-Prieto, Jaime, Serrano del Valle, Alfonso, David Sanz-Rosa, Andrés Pun-García, Sanz Rosa, David, Garcia-Ruiz, Jose M, José M García-Ruiz, Fuster, Valentin, Fernandez-Jimenez, Rodrigo, Inés García-Lunar, Pun García, Andrés, Del Valle, Alfonso Serrano, García Lunar, Inés, Fernández Jiménez, Rodrigo, Garcia-Lunar, Ines, Sreeramkumar, Vinatha, Rodrigo Fernández-Jiménez, Alfonso Serrano del Valle, Garcia-Ruiz, Jose M., Villena Gutiérrez, Rocío, Esther Bernardo, Ibáñez, Borja, Borja Ibanez, Rafael Bourio-Martínez, Bourio Martínez, Rafael, Pizarro, Gonzalo, Antonio Fernández-Ortiz, Andrés Hidalgo, Crainiciuc, Georgiana, Sanz-Rosa, David, Gonzalo Pizarro, Gomez, Monica, Jaime García-Prieto, Hidalgo, Andres, Fernandez-Ortiz, Antonio, García Ruiz, José María, Del Valle, Alfonso S., Vinatha Sreeramkumar, Valentín Fuster, Villena-Gutierrez, Rocio, Bourio-Martinez, Rafael, Bernardo, Esther, Pun-Garcia, Andres, Rocío Villena-Gutiérrez, García Prieto, Jaime, Mónica Gómez, Georgiana Crainiciuc   +46 more
core   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

ESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani, Petar Seferovic, Gianluigi Savarese, Ilaria Spoletini, Egidio Imbalzano, Antoni Bayes‐Genis, Ewa Jankowska, Michele Senni, Marco Metra, Ovidiu Chioncel, Andrew J. S. Coats, Giuseppe M. C. Rosano   +11 more
wiley   +1 more source

Phenotyping patients with chronic obstructive pulmonary disease and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 900-911, April 2025.
Central illustration. Abbreviations: ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNi, angiotensin‐receptor‐neprilysin inhibitor; CI, confidence interval; COPD, chronic obstructive pulmonary disease; CRT, cardiac resynchronization therapy; CV, cardiovascular; EF, ejection fraction; eGFR, estimated glomerular ...
Peter Moritz Becher, Felix Lindberg, Lina Benson, Camilla Hage, Ulf Dahlström, Stephan Rosenkranz, Francesco Cosentino, Giuseppe M.C. Rosano, Stefan Blankenberg, Paulus Kirchhof, Frieder Braunschweig, Lars H. Lund, Gianluigi Savarese   +12 more
wiley   +1 more source

Use of beta-blockers for the treatment of cardiovascular diseases: focus on metoprolol

Медицинский совет, 2015
The article tells about the mechanisms of action of beta-blockers. Pharmacokinetic, pharmacodynamic and interaction properties of metoprolol are discussed.
O. D. Ostroumova, V. M. Fomina
doaj   +1 more source

A Pharmacogenomics‐Guided Antihypertensive Strategy for Blood Pressure Reduction in Rural China: A Cluster‐Randomized Controlled Trial

Health Care Science, EarlyView.
This manuscript reports the findings from the Pharmacogenomic‐guided Antihypertensive Strategy Trial study amidst the deteriorating blood pressure control observed globally during the COVID‐19 pandemic. A pharmacogenomics‐guided strategy achieved a 98.4% blood pressure control rate at 4 weeks in rural China.
Wangjun Qin, Mengke Yu, Ying Zhu, Queran Lin, Limei Yin, Guisheng Liu, Yaping Wang, Guangqiang Lu, Xiaofei Liu, Pengmei Li, Xudong Kong, Li Zhao, Kun Tang, Jiangli Jin, Yu Xiong, Yingnan Zhao, Yan Yan, Bo Li, Azeem Majeed, Xianbo Zuo, Yue Qiu, Jiantuo Yu, Lihong Liu   +22 more
wiley   +1 more source

Heritability of metoprolol and torsemide pharmacokinetics

, 2015
Genetic variation in the pharmacokinetics of metoprolol and torsemide due to polymorphisms in CYP2D6, CYP2C9, and OATP1B1 has been extensively studied.
Hofmann, U. G., Hjelmborg, Jacob v. B.; id_orcid, S Möller, Hofmann, Ute, MV Tzvetkov, Sachse-Seeboth, Cordula, Möller, S., J Brockmöller, Schwab, M., Matthaei, Johannes, Halekoh, U., Sehrt, Daniel, JB Hjelmborg, Schwab, Matthias, M Schwab, Hjelmborg, Jakob B., D Sehrt, Tzvetkov, Mladen, U Halekoh, Tzvetkov, Mladen Vassilev, J Matthaei, Möller, Sören; id_orcid, C Sachse‐Seeboth, R Kerb, U Hofmann, Brockmöller, Jürgen, Kerb, Reinhold, Halekoh, Ulrich   +27 more
core   +1 more source

Association between P-pulmonale and respiratory morbidity in COPD: a secondary analysis of the BLOCK-COPD trial

BMC Pulmonary Medicine, 2023
Rationale Pulmonary hypertension (PH) in COPD confers increased risk of exacerbations (ECOPD). Electrocardiogram (ECG) indicators of PH are prognostic both in PH and COPD. In the Beta-Blockers for the Prevention of Acute Exacerbations of COPD (BLOCK-COPD)
R. Chad Wade, Takudzwa Mkorombindo, Sharon X. Ling, Erika. S. Helgeson, David M. MacDonald, Krystle Pew, Helen Voelker, Vera Bittner, Ken M. Kunisaki, Matthew R. Lammi, Mark. T. Dransfield   +10 more
doaj   +1 more source