Measurements, Thermodynamic Modeling, and a Hydrogen Bonding Study on the Solubilities of Metoprolol Succinate in Organic Solvents [PDF]
The solubilities of metoprolol succinate (a cardioselective β1 adrenergic receptor) in methanol, ethanol, n-propanol, isopropanol, n-butanol, ethyl acetate, and acetone were measured at temperatures ranging from (278.2 to 318.2) K using a solid ...
Xianrui Liang
exaly +4 more sources
Effects of low-dose metoprolol succinate sustained-release tablets on patients with paroxysmal atrial fibrillation undergoing circumferential pulmonary vein isolation: a retrospective cohort study [PDF]
Background The atria, particularly those near the pulmonary vein ostium, have numerous autonomic neural plexuses. Circumferential pulmonary vein isolation (CPVI) can reduce heart rate variability (HRV) parameters.
Lijiang Ding +3 more
doaj +3 more sources
Ten-Year Results of a Single-Center Trial Investigating Heart Rate Control with Ivabradine or Metoprolol Succinate in Patients After Heart Transplantation [PDF]
Aims: Sinus tachycardia after heart transplantation (HTX) due to cardiac graft denervation is associated with reduced post-transplant survival and requires adequate treatment.
Fabrice F. Darche +6 more
doaj +3 more sources
Azelnidipine is a novel dihydropyridine calcium channel antagonist and Metoprolol succinate is a beta blocker, this combination was approved by CDSCO for Phase III clinical trial in April 2021.
Hitanshi Darji, Zarna Dedania
exaly +4 more sources
Amiodarone vs. metoprolol succinate in HFrEF complicated with persistent atrial fibrillation with rapid ventricular response: A prospective observational study [PDF]
Backgroundβ-blockers have been recommended for patients with heart failure (HF) and atrial fibrillation (AF), but studies have shown that β-blockers do not reduce all-cause mortality or cardiovascular mortality in patients with HF and AF.ObjectiveTo ...
Yongrong Liu, Yali Hong
doaj +2 more sources
Development of a Scalable Process of Film-Coated bi-Layer Tablet Containing Sustained-Release Metoprolol Succinate and Immediate-Release Amlodipine Besylate [PDF]
The development of new drugs that combine active ingredients for the treatment hypertension is critically essential owing to its offering advantages for both patients and manufacturers.
Nguyen Thi Linh Tuyen +3 more
doaj +2 more sources
Interaction of Palmitic Acid with Metoprolol Succinate at the Binding Sites of Bovine Serum Albumin [PDF]
Purpose: The aim of this study was to characterize the binding profile as well as to notify the interaction of palmitic acid with metoprolol succinate at its binding site on albumin.
Mashiur Rahman +3 more
doaj +2 more sources
A stability-indicating potentiometric platform for assaying Metoprolol succinate and felodipine in their tablets and human plasma. [PDF]
Solid contact electrodes are prevalent in analytical applications due to their superior performance compared to traditional electrodes. Nonetheless, these electrodes have been observed to develop a water layer, which compromises their stability.
El Fiky HA +5 more
europepmc +2 more sources
Comparison of the efficacy, safety, and tolerability of the FDC of telmisartan + bisoprolol with telmisartan + metoprolol succinate ER combination therapy for stage 1 and stage 2 hypertension: A double-blind, multicentric, phase-III clinical study. [PDF]
Aim The present study compared the safety, efficacy, and tolerability of the new fixed-dose combination (FDC) of telmisartan 40 mg + bisoprolol 5 mg (TBP) tablets with the existing comparator FDC telmisartan 40 mg + metoprolol succinate ER 50 mg (TMS ...
Wander GS +11 more
europepmc +2 more sources
Comparative Effectiveness of Bisoprolol, Carvedilol, and Metoprolol Succinate in Patients with Heart Failure and CKD. [PDF]
Huang CW +7 more
europepmc +2 more sources

