Results 21 to 30 of about 78,579 (196)
Cardiovascular Diabetology, 2011 Background Carvedilol has been shown to be superior to metoprolol tartrate to improve clinical outcomes in patients with heart failure (HF), yet the mechanisms responsible for these differences remain unclear.
Køber Lars +8 more
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Management of Ablation-Refractory Atrial Fibrillation During Pregnancy. [PDF]
Case Rep MedDevelopment of new atrial fibrillation (AF) is uncommon in pregnancy with an incidence of 0.03%. The occurrence of drug‐refractory AF during pregnancy in individuals with structurally normal hearts is even rarer, and there are no reports of ablation‐refractory AF during pregnancy in the literature.
Abu Za'nouneh F +4 more
europepmc +2 more sources
Mavacamten as an Effective Treatment for HCM With Latent Exercise-Induced Obstruction: A Case Report. [PDF]
Case Rep CardiolBackground Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by hypertrophy of the left ventricle that can lead to significant symptoms, particularly with exercise. For patients with HCM who demonstrate obstructive physiology, the first‐in‐class targeted cardiac specific myosin inhibitor, mavacamten, has been found to reduce the ...
Murthy N +4 more
europepmc +2 more sources
Бюллетень сибирской медицины, 2022 Aim. To study the prognostic value of high serum concentration of soluble ST2 protein (sST2) in the development of cardiovascular events after endovascular myocardial revascularization and the possibility of using this biomarker as a target for β-blocker
E. V. Grakova +5 more
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EFFECT OF ESSENTIAL OILS ON TRANSDERMAL PERMEATION OF METOPROLOL SUCCINATE [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2021 The objective of the present study was to prepare a matrix-type transdermal drug delivery system containing metoprolol succinate and to evaluate the effect of essential oils on transdermal permeation of drug.
B. N. Suhagia +5 more
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{2-Hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}isopropylammonium hemisuccinate
Acta Crystallographica Section E, 2009 Metoprolol, a widely used adrenoreceptor blocking drug, is commonly administered as the succinate or tartrate salt. The structure of metoprolol succinate, C15H26NO3+·0.5C4H4O42−, is characterized by the presence of ribbons in which ...
Gianluca Bartolucci +3 more
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WHAT DOES PROVIDE A CLINICAL EFFICACY OF METOPROLOL?
Рациональная фармакотерапия в кардиологии, 2016 Relationship of metoprolol clinical efficacy with its different salts (tartrate, succinate, fumarate) as well as its presentations (tablets with immediate, controlled or sustained release) is analyzed.
E. V. Kuleshova
doaj +1 more source
Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals. [PDF]
Clin Pharmacol TherData science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
Tan GSQ +6 more
europepmc +2 more sources
Journal of Pharmaceutical Analysis, 2019 Aryloxypropanolamine is an essential structural scaffold for a variety of β-adrenergic receptor antagonists such as metoprolol. Molecules with such a structural motif tend to degrade into α, β–hydroxypropanolamine impurities via a radical–initiated ...
Qun Xu, Shane Tan
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To estimate metoprolol succinate effect on regulatory and adaptive status (RAS) of patients with сhronic heart failure (CHF) functional class (FC) I and arterial hypertension (HT) I-II stages. Material and methods. 51 patients with CHF FC I and HT I-
V. G. Tregubov +2 more
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