Results 31 to 40 of about 78,579 (196)

Use of beta-blockers for the treatment of cardiovascular diseases: focus on metoprolol

Медицинский совет, 2015
The article tells about the mechanisms of action of beta-blockers. Pharmacokinetic, pharmacodynamic and interaction properties of metoprolol are discussed.
O. D. Ostroumova, V. M. Fomina
doaj   +1 more source

Effects of Metoprolol on Periprocedural Myocardial Infarction After Percutaneous Coronary Intervention (Type 4a MI): An Inverse Probability of Treatment Weighting Analysis

Frontiers in Cardiovascular Medicine, 2021
Background: Metoprolol is the most used cardiac selective β-blocker and has been recommended as a mainstay drug in the management of acute myocardial infarction (AMI). However, the evidence supporting this regimen in periprocedural myocardial infarction (
Duanbin Li, Duanbin Li, Ya Li, Ya Li, Maoning Lin, Maoning Lin, Wenjuan Zhang, Guosheng Fu, Guosheng Fu, Zhaoyang Chen, Chongying Jin, Chongying Jin, Wenbin Zhang, Wenbin Zhang   +13 more
doaj   +1 more source

Stability Indicating Method Development and Validation of Metoprolol Succinate and Empagliflozin by RP-HPLC in Synthetic Mixture

International Journal for Research in Applied Science and Engineering Technology
This review article focuses on the development and validation of a stability-indicating RP-HPLC method for the simultaneous estimation of Metoprolol Succinate and Empagliflozin in a synthetic mixture.
Vandit Patel
semanticscholar   +1 more source

Evaluation of efficacy of metoprolol in patients having heart failure with preserved ejection fraction: A randomized, double-blind, placebo-controlled pilot trial

Perspectives in Clinical Research, 2017
Background: There is a lack of evidence-based therapies for the treatment of heart failure (HF) with preserved ejection fraction (HFpEF). Beta blockers may provide some benefit in HFpEF due to their proven role in HF with reduced ejection fraction.
Niti Mittal, Nusrat Shafiq, Sreenivas Reddy, Samir Malhotra, Savita Kumari, Subhash Varma   +5 more
doaj   +1 more source

Spectrophotometric Simultaneous Equation and Area under the Curve Methods for Estimation of Metoprolol Succinate and Telmisartan in Pure Drugs and its Combined Marketed Formulation

Indian Journal of Pharmaceutical Education and Research
Background: Telmisartan-metoprolol succinate formulations treat hypertension. The primary goal was to develop and evaluate a UV-spectrophotometric method for estimating telmisartan and metoprolol succinate in a combination tablet dosage form in ...
Vivek Sharma, Rina Das, D. Mehta, Anu Chaudhary, Samir Patel, Archita Jayendra kumar Patel   +5 more
semanticscholar   +1 more source

Impella‐Assisted High‐Risk Percutaneous Coronary Intervention in Cardiogenic Shock With Low‐Flow, Low‐Gradient Aortic Stenosis and Multivessel Coronary Artery Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Patients with cardiogenic shock, low‐flow, low‐gradient aortic stenosis, and multivessel coronary artery disease who are ineligible for surgery present a major therapeutic challenge. Percutaneous mechanical circulatory support may facilitate revascularization in this high‐risk population. A 69‐year‐old man presented after a mechanical fall and
Douni Roger, Waleed Shaker, Zan Siddiqi, George Abela   +3 more
wiley   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Development of a 3D printed multiple unit particle system (MUPS) containing metoprolol succinate.

European Journal of Pharmaceutical Sciences
This study presents the development and characterisation of dual extrusion 3D printed multiple unit particle system (MUPS) tablets incorporating metoprolol succinate.
Lee Roy Oldfield, Björn Fischer, Tobias Auel, Anne Seidlitz   +3 more
semanticscholar   +1 more source

Paradoxical Rise in Pulmonary Artery Pressure Following Successful Mavacamten Therapy for Obstructive Hypertrophic Cardiomyopathy: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT A paradoxical rise in pulmonary artery pressure on follow‐up echocardiography after successful mavacamten therapy for obstructive hypertrophic cardiomyopathy (oHCM) prompted right heart catheterization, which demonstrated combined pre‐ and post‐capillary pulmonary hypertension and guided the decision to continue mavacamten while withholding ...
Mengdian Zhang
wiley   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, Volume 4, Issue 2, June 2026.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source