Results 21 to 30 of about 31,613 (220)
The Journal of Headache and Pain, 2017 Background Beta-blockers are a first choice migraine preventive medication. So far it is unknown how they exert their therapeutic effect in migraine. To this end we examined the neural effect of metoprolol on trigeminal pain processing in 19 migraine ...
Julia M. Hebestreit, Arne May
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Discontinuation and dose adjustment of metoprolol after metoprolol-paroxetine/fluoxetine co-prescription in Dutch elderly [PDF]
, 2018 PurposeCo-prescription of paroxetine/fluoxetine (a strong CYP2D6 inhibitor) in metoprolol (a CYP2D6 substrate) users is common, but data on the clinical consequences of this drug-drug interaction are limited and inconclusive.
Wang, Yuanyuan +10 more
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Revista Colombiana de Cardiología, 2012 realizar una evaluación de costo-efectividad del uso de metoprolol succinato frente a metoprolol tartrato y carvedilol en el tratamiento de pacientes con insuficiencia cardiaca congestiva e hipertensión arterial en Colombia, desde la perspectiva del ...
Martín Romero, MD., MSc. +1 more
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Effect of hesperetin on the pharmacokinetics of metoprolol succinate in rats
Future Journal of Pharmaceutical Sciences, 2023 Background Metoprolol is a substrate of CYP3A4, 2B6, CYP2D6, CYP2C9, and p-glycoprotein (p-gp). Hesperetin was reported as an inhibitor of cytochrome P-450 (CYP) enzymes and p-gp. The objective of this study was to investigate the effect of hesperetin on
Ravindra Babu Pingili +5 more
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Design of experiments methodology in studying near-infrared spectral information of model intact tablets : simultaneous determination of metoprolol tartrate and hydrochlorothiazide in solid dosage forms and powder compressibility assessment using near-infrared spectroscopy [PDF]
, 2015 Near-infrared spectroscopy (NIRS) is applied in pharmaceutical industry for monitoring drug content during tablet manufacturing process. NIRS method, once developed and validated, is used over years and it is of critical importance to insure method ...
Vranic, Branko Z.
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Coronary collateral perfusion in patients with coronary artery disease: effect of metoprolol [PDF]
, 2004 BACKGROUND The use of ultrathin Doppler angioplasty guidewires has made it possible to measure collateral flow quantitatively. Pharmacologic interventions have been shown to influence collateral flow and, thus, to affect myocardial ischaemia ...
Hess, Otto M +5 more
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Journal of Pharmacy & Pharmaceutical Sciences, 2019 Purpose: Preliminary study results have shown that rats with non-alcoholic fatty liver disease (NAFLD) induced by 1% orotic acid-containing diet have decreased hepatic CYP2D activity.
Won Seok Bang +4 more
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Clinical and Translational Science, 2023 Females present a higher risk of adverse drug reactions. Sex‐related differences in drug concentrations may contribute to these observations but they remain understudied given the underrepresentation of females in clinical trials.
Jessica Hindi +13 more
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Effects of Metoprolol and Nebivolol on Exercise Blood Pressure in Patients with Mild Hypertension
The Scientific World Journal, 2013 Objectives. We planned to compare the impact of two beta blockers, metoprolol and nebivolol, on arterial blood pressure during exercise in patients with mild hypertension. Methods.
Huseyin Ugur Yazici +3 more
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Development, validation and application of the Basel phenotyping cocktail [PDF]
, 2015 Personalized therapy is a matter of current discussion in the medical community. It consists of adapting the choice of a drug and its posology to the specific profile of a subject (genotype and phenotype) or to its disease (i.e. specific cancer biology).
Donzelli, Massimiliano
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