Results 21 to 30 of about 34,481 (211)
Phytomedicine Plus, 2023 Background: Many studies have shown that Shensong Yangxin capsule (SSYX)–metoprolol combination has efficacy in treating cardiac arrhythmia. However, it is still lacking large randomized controlled trials and comprehensive and rigorous systematic ...
Xinrui Wang +6 more
doaj +1 more source
Poly(vinyl alcohol)-based membranes for metoprolol transdermal delivery
, 2021 In this work controlled release devices for transdermal administration of metoprolol were developed. Poly(vinyl alcohol) and poly(vinyl pyrrolidone) were used for producing membranes by solvent- casting technique.
SA Aljlil +4 more
core +1 more source
The Journal of Headache and Pain, 2017 Background Beta-blockers are a first choice migraine preventive medication. So far it is unknown how they exert their therapeutic effect in migraine. To this end we examined the neural effect of metoprolol on trigeminal pain processing in 19 migraine ...
Julia M. Hebestreit, Arne May
doaj +1 more source
Design of experiments methodology in studying near-infrared spectral information of model intact tablets : simultaneous determination of metoprolol tartrate and hydrochlorothiazide in solid dosage forms and powder compressibility assessment using near-infrared spectroscopy [PDF]
, 2015 Near-infrared spectroscopy (NIRS) is applied in pharmaceutical industry for monitoring drug content during tablet manufacturing process. NIRS method, once developed and validated, is used over years and it is of critical importance to insure method ...
Vranic, Branko Z.
core +1 more source
Revista Colombiana de Cardiología, 2012 realizar una evaluación de costo-efectividad del uso de metoprolol succinato frente a metoprolol tartrato y carvedilol en el tratamiento de pacientes con insuficiencia cardiaca congestiva e hipertensión arterial en Colombia, desde la perspectiva del ...
Martín Romero, MD., MSc. +1 more
doaj +1 more source
Discontinuation and dose adjustment of metoprolol after metoprolol-paroxetine/fluoxetine co-prescription in Dutch elderly [PDF]
, 2018 PurposeCo-prescription of paroxetine/fluoxetine (a strong CYP2D6 inhibitor) in metoprolol (a CYP2D6 substrate) users is common, but data on the clinical consequences of this drug-drug interaction are limited and inconclusive.
Wang, Yuanyuan +10 more
core +2 more sources
Effect of hesperetin on the pharmacokinetics of metoprolol succinate in rats
Future Journal of Pharmaceutical Sciences, 2023 Background Metoprolol is a substrate of CYP3A4, 2B6, CYP2D6, CYP2C9, and p-glycoprotein (p-gp). Hesperetin was reported as an inhibitor of cytochrome P-450 (CYP) enzymes and p-gp. The objective of this study was to investigate the effect of hesperetin on
Ravindra Babu Pingili +5 more
doaj +1 more source
Neutrophil stunning by metoprolol reduces infarct size [PDF]
, 2017 The β1-adrenergic-receptor (ADRB1) antagonist metoprolol reduces infarct size in acute myocardial infarction (AMI) patients. The prevailing view has been that metoprolol acts mainly on cardiomyocytes.
Garcia-Prieto, Jaime +46 more
core +1 more source
Journal of Pharmacy & Pharmaceutical Sciences, 2019 Purpose: Preliminary study results have shown that rats with non-alcoholic fatty liver disease (NAFLD) induced by 1% orotic acid-containing diet have decreased hepatic CYP2D activity.
Won Seok Bang +4 more
doaj +1 more source
Clinical and Translational Science, 2023 Females present a higher risk of adverse drug reactions. Sex‐related differences in drug concentrations may contribute to these observations but they remain understudied given the underrepresentation of females in clinical trials.
Jessica Hindi +13 more
doaj +1 more source