Results 51 to 60 of about 34,481 (211)

Use of beta-blockers for the treatment of cardiovascular diseases: focus on metoprolol

Медицинский совет, 2015
The article tells about the mechanisms of action of beta-blockers. Pharmacokinetic, pharmacodynamic and interaction properties of metoprolol are discussed.
O. D. Ostroumova, V. M. Fomina
doaj   +1 more source

Heritability of metoprolol and torsemide pharmacokinetics

, 2015
Genetic variation in the pharmacokinetics of metoprolol and torsemide due to polymorphisms in CYP2D6, CYP2C9, and OATP1B1 has been extensively studied.
Hofmann, U. G., Hjelmborg, Jacob v. B.; id_orcid, S Möller, Hofmann, Ute, MV Tzvetkov, Sachse-Seeboth, Cordula, Möller, S., J Brockmöller, Schwab, M., Matthaei, Johannes, Halekoh, U., Sehrt, Daniel, JB Hjelmborg, Schwab, Matthias, M Schwab, Hjelmborg, Jakob B., D Sehrt, Tzvetkov, Mladen, U Halekoh, Tzvetkov, Mladen Vassilev, J Matthaei, Möller, Sören; id_orcid, C Sachse‐Seeboth, R Kerb, U Hofmann, Brockmöller, Jürgen, Kerb, Reinhold, Halekoh, Ulrich   +27 more
core   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Angiogenic biomarker concentrations and their relation to coronary atherosclerosis in women with a history of preeclampsia: Findings from the CPH‐PRECIOUS study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This study demonstrates that women with prior preeclampsia had significantly higher concentrations of PlGF when CT‐assessed coronary atherosclerosis was present years following the index pregnancy, whereas no difference was found for concentrations of sFlt‐1.
Signe Højstrup Bessing, Maria Guldbrandt Hauge, Jesper James Linde, Marianne Johansen, Anne Ersbøll, Klaus Fuglsang Kofoed, Andreas Fuchs, Per Ejlstrup Sigvardsen, Finn Gustafsson, Mille Kirk, Line Rode, Peter Damm   +11 more
wiley   +1 more source

Pharmacokinetics of metoprolol tartrate in patients with and without controlled arterial hypertension

Фармакокинетика и Фармакодинамика
Background. Metoprolol is a selective beta-blocker that is most commonly used in the pharmacotherapy of cardiovascular diseases, including hypertension (AH).Objective.
S. V. Seleznev, A. V. Shchulkin, P. Yu. Mylnikov, N. V. Enenkov   +3 more
doaj   +1 more source

Measurements, Thermodynamic Modeling, and a Hydrogen Bonding Study on the Solubilities of Metoprolol Succinate in Organic Solvents

Molecules, 2018
The solubilities of metoprolol succinate (a cardioselective β1 adrenergic receptor) in methanol, ethanol, n-propanol, isopropanol, n-butanol, ethyl acetate, and acetone were measured at temperatures ranging from (278.2 to 318.2) K using a solid ...
Jian Shen, Xianrui Liang, Hao Lei
doaj   +1 more source

Association between P-pulmonale and respiratory morbidity in COPD: a secondary analysis of the BLOCK-COPD trial

BMC Pulmonary Medicine, 2023
Rationale Pulmonary hypertension (PH) in COPD confers increased risk of exacerbations (ECOPD). Electrocardiogram (ECG) indicators of PH are prognostic both in PH and COPD. In the Beta-Blockers for the Prevention of Acute Exacerbations of COPD (BLOCK-COPD)
R. Chad Wade, Takudzwa Mkorombindo, Sharon X. Ling, Erika. S. Helgeson, David M. MacDonald, Krystle Pew, Helen Voelker, Vera Bittner, Ken M. Kunisaki, Matthew R. Lammi, Mark. T. Dransfield   +10 more
doaj   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

Análisis de costo efectividad del uso de metoprolol succinato en el tratamiento de la hipertensión arterial y la falla cardiaca en Colombia Analysis of cost effectiveness of the use of metoprolol succinate in the treatment of hypertension and heart failure in Colombia

Revista Colombiana de Cardiología, 2012
Objetivo: realizar una evaluación de costo-efectividad del uso de metoprolol succinato frente a metoprolol tartrato y carvedilol en el tratamiento de pacientes con insuficiencia cardiaca congestiva e hipertensión arterial en Colombia, desde la ...
Martín Romero, Carlos H Arango
doaj