Results 51 to 60 of about 1,302,221 (298)

Geometry of Metrics

open access: yes, 2010
During the past thirty years hyperbolic type metrics have become popular tools also in modern mapping theory, e.g., in the study of quasiconformal and quasiregular maps in the euclidean $n$-space. We study here several metrics that one way or another are related to modern mapping theory and point out many open problems dealing with the geometry of such
openaire   +3 more sources

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Extracting the quantum geometric tensor of an optical Raman lattice by Bloch-state tomography

open access: yesPhysical Review Research, 2023
In Hilbert space, the geometry of the quantum state is identified by the quantum geometric tensor (QGT), whose imaginary part is the Berry curvature and whose real part is the quantum metric tensor.
Chang-Rui Yi   +8 more
doaj   +1 more source

Weyl-ambient geometries

open access: yesNuclear Physics B, 2023
Weyl geometry is a natural extension of conformal geometry with Weyl covariance mediated by a Weyl connection. We generalize the Fefferman-Graham (FG) ambient construction for conformal manifolds to a corresponding construction for Weyl manifolds.
Weizhen Jia   +2 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Geometry of Centroaffine Surfaces in R5

open access: yes, 2015
. We use Cartan’s method of moving frames to compute a complete set of local invariants for nondegenerate, 2-dimensional centroaffine surfaces in R5 \ {0} with nonde-generate centroaffine metric.
Jeanne N. Clelland   +3 more
core   +1 more source

The Geometry of Conventionality [PDF]

open access: yes, 2013
Hans Reichenbach famously argued that the geometry of spacetime is conventional in relativity theory, in the sense that one can freely choose the spacetime metric so long as one is willing to postulate a "universal force field".
Weatherall, James Owen   +3 more
core   +1 more source

Geometrothermodynamics as a singular conformal thermodynamic geometry

open access: yesPhysics Letters B, 2019
In this letter, we first redefine our formalism of the thermodynamic geometry introduced in [1,2] by changing coordinates of the thermodynamic space by means of Jacobian matrices.
Seyed Ali Hosseini Mansoori   +1 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy