Results 131 to 140 of about 4,342,124 (307)
Metric and Symmetric Spaces [PDF]
Proceedings of the American Mathematical Society, 1974 In this paper we give an alternative proof, without reference to Urysohn’s lemma, of the metrization theorem of Bing [ 2 ], Nagata [ 6 ], and Smirnov [ 8 ] via the theory of symmetric spaces as developed by H ...
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Fuzzy Isometry and Standard Modular Structures in Modular Fuzzy Metric Spaces
Muthanna Journal of Pure ScienceThis paper investigates the relationship between modular metric spaces and modular fuzzy metric spaces by introducing and studying the concept of the standard modular fuzzy metric space.
Mohammed Jawad Kadhim
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Deep hierarchical embedding for simultaneous modeling of GPCR proteins in a unified metric space. [PDF]
Sci Rep, 2021 Lee T, Lee S, Kang M, Kim S.
europepmc +1 more source
Energy-based model of forming subgroups on finite metric space [PDF]
, 2009 Local interactions between particles of a collection causes all particles to reorganize in new positions. The purpose of this paper is to construct an energy-based model of self-organizing subgroups, which describes the behavior of singular local moves ...
Zahri, Mostafa
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Partial Fuzzy Soft Metric Space
Journal of Applied Science and EngineeringMatthew introduced a partial metric, sometimes known as a non-zero self-distance. This paper seeks to extend Matthew’s notion to the fuzzy soft universe and create a partial fuzzy soft metric.
Younes Hazem Thiyab, Ghaith Ali Salom
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source