Results 61 to 70 of about 202,228 (310)

Function valued metric spaces [PDF]

open access: yesSurveys in Mathematics and its Applications, 2010
In this paper we introduce the notion of an ℱ-metric, as a function valued distance mapping, on a set X and we investigate the theory of ℱ-metrics paces.
Madjid Mirzavaziri
doaj  

A new extension to the controlled metric type spaces endowed with a graph

open access: yesAdvances in Difference Equations, 2021
In this paper, we initiate a new extension of b-metric spaces, called controlled metric-like spaces, by changing the condition [ ℘ ( s , r ) = 0 ⇔ s = r ] by  [ ℘ ( s , r ) = 0 ⇒ s = r ] $$ \bigl[\wp (s,r)=0 \Leftrightarrow s=r\bigr]\quad \text{by ...
Nabil Mlaiki   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A COMPLETION THEOREM FOR COMPLEX VALUED S-METRIC SPACE

open access: yesBarekeng
Any complex valued S-metric space where each Cauchy sequence converges to a point in this space is said to be complete. However, there are complex valued S-metric spaces that are incomplete but can be completed.
Mariatul Kiftiah   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

METRIC PROJECTIONS IN LINEAR METRIC SPACES

open access: yesDemonstratio Mathematica, 1990
Summary: Various properties of the metric projection are known in normed linear spaces. \textit{G. Pantelidis} [Math. Ann. 184, 30--48 (1969; Zbl 0175.42001)] discussed some of these properties in linear metric spaces. In this paper we also discuss some necessary and sufficient conditions for the metric projections to be continuous and Lipschitzian in ...
openaire   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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