Results 71 to 80 of about 1,365,357 (275)

Continuous and Uniform Continuous Mappings on a Standard Fuzzy Metric Spaces [PDF]

Engineering and Technology Journal, 2014
In this paper we introduced the definition of standard fuzzy metric spaces then we discussed several properties of this space after some illustrative examples are given. Then we defined a continuous mapping from standard fuzzy metric space (X,M_X,*) into
Jehad R.Kider, Zeina A.Hussain
doaj   +1 more source

Causal geometries and third-order ordinary differential equations [PDF]

, 2009
We discuss contact invariant structures on the space of solutions of a third-order ordinary differential equation. Associated to any third-order differential equation modulo contact transformations, Chern introduced a degenerate conformal Lorentzian ...
Holland, Jonathan, Sparling, George
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

METRIC PROJECTIONS IN LINEAR METRIC SPACES

Demonstratio Mathematica, 1990
Summary: Various properties of the metric projection are known in normed linear spaces. \textit{G. Pantelidis} [Math. Ann. 184, 30--48 (1969; Zbl 0175.42001)] discussed some of these properties in linear metric spaces. In this paper we also discuss some necessary and sufficient conditions for the metric projections to be continuous and Lipschitzian in ...
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

On Parametric S-Metric Spaces and Fixed-Point Type Theorems for Expansive Mappings

Journal of Mathematics, 2016
We introduce the notion of a parametric S-metric space as generalization of a parametric metric space. Using some expansive mappings, we prove a fixed-point theorem on a parametric S-metric space.
Nihal Taş, Nihal Yılmaz Özgür
doaj   +1 more source

Partial b_{v}(s) and b_{v}({\theta}) metric spaces and related fixed point theorems

, 2018
In this paper, we introduced two new generalized metric spaces called partial b_{v}(s) and b_{v}({\theta}) metric spaces which extend b_{v}(s) metric space, b-metric space, rectangular metric space, v-generalized metric space, partial metric space ...
Isik, Irfan, Karahan, Ibrahim
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source