Results 91 to 100 of about 234,437 (318)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Hyperconvexity and endpoints in T₀-quasi-metric spaces
, 2013 Over the last decades much progress has been made in the investigation of hyperconvexity in metric spaces. Recently Kemajou and others have published an article concerning hyperconvexity in T₀-quasi-metric spaces.
Haihambo, Paulus
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Balls in generalizations of metric spaces
Journal of Inequalities and Applications, 2016 This paper discusses balls in partial b-metric spaces and cone metric spaces, respectively. Let ( X , p b ) $(X,p_{b})$ be a partial b-metric space in the sense of Mustafa et al. For the family △ of all p b $p_{b}$ -open balls in ( X , p b ) $(X,p_{b})$ ,
Xun Ge, Shou Lin
doaj +1 more source
METRIC PROJECTIONS IN LINEAR METRIC SPACES
Demonstratio Mathematica, 1990 Summary: Various properties of the metric projection are known in normed linear spaces. \textit{G. Pantelidis} [Math. Ann. 184, 30--48 (1969; Zbl 0175.42001)] discussed some of these properties in linear metric spaces. In this paper we also discuss some necessary and sufficient conditions for the metric projections to be continuous and Lipschitzian in ...
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Convexity in quasi-metric spaces
, 2012 Includes abstract.Includes bibliographical references.The principal aim of this thesis is to investigate the existence of an injective hull in the categories of T-quasi-metric spaces and of T-ultra-quasi-metric spaces with nonexpansive ...
Otafudu, Olivier Olela
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Notices of the American Mathematical Society, 2020 This note is a survey of Analysis on Metric spaces, in connection with the upcoming AMS Mathematics Research Communities program in June 2020.
Bonk, Mario +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Fixed Point Theorems in $ b$-Rectangular Metric Spaces
Universal Journal of Mathematics and Applications, 2020 The concept of $ b$-rectangular metric space is introduced as a generalization of $ b $-metric space and rectangular (generalized) metric space. In this paper, we introduce generalized almost contraction for two mappings and prove common fixed point ...
Vildan Öztürk
doaj +1 more source