Results 101 to 110 of about 234,437 (318)

Metric for object association in the Keplerian orbits space

open access: yes, 2020
Orbit determination of space debris objects in the context of space surveillance is often performed by associating several sequences of observations related to the same object.
Schildknecht, T., Vananti, A.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Fixed Point Results for Nonlinear F-Contractions in Composed S-Metric Spaces

open access: yesJournal of Function Spaces
In this paper, we introduce the concept of composed S-metric space as a new generalization of S-metric space and Sb-metric space. We present some examples showing that a composed S-metric space is a generalization of various types of abstract spaces, and
Chol Jin Kil   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Fixed point theorems in a new type of modular metric spaces

open access: yesFixed Point Theory and Applications, 2018
In this paper, considering both a modular metric space and a generalized metric space in the sense of Jleli and Samet (Fixed Point Theory Appl. 2015:61, 2015), we introduce a new concept of generalized modular metric space.
Duran Turkoglu, Nesrin Manav
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The Effect of Metric Space on the Results of Graph Based Colour Image Segmentation

open access: yes, 2012
This paper deals with the impact of the metric space on the results of colour image segmentation algorithm. Distance and similarity measures are important tasks for quality of colour image segmentation.
Patrik Kamencay   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Related fixed point theorems on two complete and compact metric spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1998
A new related fixed point theorem on two complete metric spaces is obtained. A generalization is given for two compact metric spaces.
R. K. Namdeo   +3 more
doaj   +1 more source

Rectangular cone b-metric spaces over Banach algebra and contraction principle

open access: yesFixed Point Theory and Applications, 2017
Rectangular cone b-metric spaces over a Banach algebra are introduced as a generalization of metric space and many of its generalizations. Some fixed point theorems are proved in this space and proper examples are provided to establish the validity and ...
Reny George   +4 more
doaj   +1 more source

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