Results 91 to 100 of about 5,790,959 (300)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Condensing on metric spaces : modeling, analysis and simulation [PDF]

open access: yes, 2009
In this work, we extend the Hegselmann and Krause (HK) model, presented in [16] to an arbitrary metric space. We also present some theoretical analysis and some numerical results of the condensing of particles in finite and continuous metric spaces.
Zahri, Mostafa
core  

Five-dimensional gauge theory and compactification on a torus [PDF]

open access: yes, 2011
We study five-dimensional minimally supersymmetric gauge theory compactified on a torus down to three dimensions, and its embedding into string/M-theory using geometric engineering.
Haghighat, B.   +6 more
core   +2 more sources

Gap Metric Robustness of Adaptive Controllers

open access: yes, 2002
We consider the construction of adaptive controllers for minimum phase linear systems which achieve non-zero robustness margins in the sense of the (linear) L2(0,∞) gap metric. The gap perturbations may be more constrained for larger disturbances and for
French, Mark
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Some Topological Characteristics of q-Rung Orthopair Fuzzy Metric Space

open access: yesAdvances in Fuzzy Systems
This paper introduced a novel concept of q-rung orthopair fuzzy (q-ROF) metric spaces, in connection with the idea of q-ROF sets, which generalizes well-known concepts of fuzzy metric spaces and intuitionistic fuzzy metric spaces.
Lariab Shahid   +4 more
doaj   +1 more source

A Note on tvs-G-Cone Metric Fixed Point Theory

open access: yesJournal of Applied Mathematics, 2012
For a tvs-G-cone metric space (𝑋,𝐺) and for the family 𝒜 of subsets of X, we introduce a new notion of the tvs-ℋ-cone metric ℋ with respect to G, and we get a fixed result for the 𝒞ℬ𝒲-tvs-G-cone-type function in a complete tvs-G-cone metric space (𝒜,ℋ ...
Ing-Jer Lin   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

A regularisation approach to causality theory for C^{1,1}Lorentzian metrics

open access: yes, 2014
We show that many standard results of Lorentzian causality theory remain valid if the regularity of the metric is reduced to C^{1,1}.
Vickers, J.A.   +7 more
core   +1 more source

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