Results 101 to 110 of about 5,790,959 (300)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Notes on separability in metric sets [PDF]
These notes consider the various topologies over metric sets generated by a selection of the metric axioms given below.
Matthews, Stephen G.
core
Constant Distortion Embeddings of Symmetric Diversities
Analysis and Geometry in Metric Spaces, 2016 Diversities are like metric spaces, except that every finite subset, instead of just every pair of points, is assigned a value. Just as there is a theory of minimal distortion embeddings of fiite metric spaces into L1, there is a similar, yet undeveloped,
Bryant David, Tupper Paul F.
doaj +1 more source
Twisted massive non-compact models
Journal of High Energy Physics, 2018 We study interacting massive N = (2, 2) supersymmetric field theories in two dimensions which arise from deforming conformal field theories with a continuous spectrum.
Songyuan Li, Jan Troost
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
M-theory exotic scalar glueball decays to mesons at finite coupling
Journal of High Energy Physics, 2018 Using the pull-back of the perturbed type IIA metric corresponding to the perturbation of [1]’s M-theory uplift of [2]’s UV-complete top-down type IIB holographic dual of large-N thermal QCD, at finite coupling, we obtain the interaction Lagrangian ...
Vikas Yadav, Aalok Misra
doaj +1 more source
Operator theory and the Carath�odory metric
Inventiones Mathematicae, 1990 Let z and w be distinct points of the bounded domain of holomorphy U in \({\mathbb{C}}^ d\). For each d-tuple M of commuting \(2\times 2\) complex matrices with joint spectrum \(\{\) z,w\(\}\), let \(\theta_ M\) denote the angle between its two (one-dimensional) eigenspaces. The author proves that the Carathéodory distance is given by \[ c_ U(z,w)=\inf
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The topology of partial metric spaces [PDF]
The T0 world of Scott's topological models used in the denotational semantics of programming languages may at first sight appear to have nothing whatever in common with the Hausdorff world of metric space theory.
Matthews, Stephen G.
core