Results 51 to 60 of about 108,606 (260)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Perturbed Graphical Metric Spaces and Fixed Point Theory [PDF]

open access: yesSahand Communications in Mathematical Analysis
Taking into account the recent view of fixed point theory as expressed by Jalali and Samet [On Banach's fixed point theorem in perturbed metric spaces, J. Appl. Anal. Comput.
Kamal Fallahi
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Simulation functions on metric fixed point theory

open access: yesJournal of Inequalities and Applications
This paper aims to generalize the primary result of Khojasteh et al. by introducing and expanding the concept of simulation functions and weak ζ-contractions under weaker conditions.
Hamid Mottaghi Golshan
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Generalizations of Hyperconvex Metric Spaces

open access: yesResults in Nonlinear Analysis, 2019
Since Khamsi found a KKM theorem for hyperconvex metric spaces in 1996, there have appeared a large number of works on them related to the KKM theory.
Sehie Park
doaj  

Fixed point theorems in a new type of modular metric spaces

open access: yesFixed Point Theory and Applications, 2018
In this paper, considering both a modular metric space and a generalized metric space in the sense of Jleli and Samet (Fixed Point Theory Appl. 2015:61, 2015), we introduce a new concept of generalized modular metric space.
Duran Turkoglu, Nesrin Manav
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Common fixed points for generalized ψ-contractions in weak non-Archimedean fuzzy metric spaces

open access: yesApplied General Topology, 2019
Fixed point theory in fuzzy metric spaces plays very important role in theory of nonlinear problems in applied science. In this paper, we prove an existence result of common fixed point of four nonlinear mappings satisfying a new type of contractive ...
Suthep Suantai   +2 more
doaj   +1 more source

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