Results 131 to 140 of about 5,269,237 (355)
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
On the boundary behavior of the holomorphic sectional curvature of the Bergman metric
Le Matematiche, 2006 We obtain a conceptually new differential geometric proof of P. F. Klembeck’s result (cf. [9]) that the holomorphic sectional curvature k g (z ) of the Bergman metric of a strictly pseudoconvex domain Ω ⊂ ℂ n approaches −4/(n + 1 ...
Elisabetta Barletta
doaj
86. Ventilator-Associated Pneumonia in Trauma Intensive Care Unit, a Dilemma in Quality Metrics [PDF]
, 2019 Rajendra Karnatak +5 more
openalex +1 more source
On flat hermitian metrics on the unit disc [PDF]
Mathematische Zeitschrift, 1970 Greene, R.E., Wu, Hung-Hsi
openaire +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Designing a TPMS metamaterial via deep learning and topology optimization
Frontiers in Mechanical EngineeringData-driven models that act as surrogates for computationally costly 3D topology optimization techniques are very popular because they help alleviate multiple time-consuming 3D finite element analyses during optimization.
Asha Viswanath +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Correlation of Metrical and Phonological Units of Language
Studia Metrica et Poetica, 2015 This paper was first published in Russian (Lekomceva 1969). Margarita Ivanovna Lekomceva (b. 1935) is a distinguished Russian linguist and semiotician, member of the Tartu-Moscow School of Semiotics. Her main research fields include Slavic, Baltic, Balkan and Indo-European phonology, rhetoric and poetics.
openaire +3 more sources
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source