Results 51 to 60 of about 998,991 (321)
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Acceleration of profile creation for three-dimensional vector video with GPGPU
In the report the optimization of image similarity metric computation method for three dimensional vector video with general-purpose computations on graphical processor unit (GPGPU) is discussed.
A. . Tsyganov
doaj +1 more source
Distances of qubit density matrices on Bloch sphere
We recall the Einstein velocity addition on the open unit ball $\B$ of $\R^{3}$ and its algebraic structure, called the Einstein gyrogroup. We establish an isomorphism between the Einstein gyrogroup on $\B$ and the set of all qubit density matrices ...
Einstein A. +3 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Rotationally Symmetric Harmonic Diffeomorphisms between Surfaces
We show the nonexistence of rotationally symmetric harmonic diffeomorphism between the unit disk without the origin and a punctured disc with hyperbolic metric on the target.
Li Chen, Shi-Zhong Du, Xu-Qian Fan
doaj +1 more source
Mathisson-Papapetrou-Tulczyjew-Dixon (MPTD) equations in the Lagrangian formulation correspond to the minimal interaction of spin with gravity. Due to the interaction, in the Lagrangian equations instead of the original metric $g$ emerges spin-dependent ...
Deriglazov, Alexei A. +1 more
core +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Schwarz-Pick Estimates for Holomorphic Mappings with Values in Homogeneous Ball
Let BX be the unit ball in a complex Banach space X. Assume BX is homogeneous. The generalization of the Schwarz-Pick estimates of partial derivatives of arbitrary order is established for holomorphic mappings from the unit ball Bn to BX associated with ...
Jianfei Wang
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

