Results 51 to 60 of about 981,969 (278)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Acceleration of profile creation for three-dimensional vector video with GPGPU

Труды Института системного программирования РАН, 2018
In the report the optimization of image similarity metric computation method for three dimensional vector video with general-purpose computations on graphical processor unit (GPGPU) is discussed.
A. . Tsyganov
doaj   +1 more source

On the Bohr inequality

, 2016
The Bohr inequality, first introduced by Harald Bohr in 1914, deals with finding the largest radius $r ...
A. Aytuna, A. Defant, A. Defant, A. Defant, A. Defant, C. Bénéteau, C. Chu, E. Bombieri, E. Bombieri, E.C. Titchmarsh, F. Bayart, G. Kresin, G. Popescu, H. Bohr, H. Hamada, H. Hamada, H.F. Bohnenblustmm, H.P. Boas, H.P. Boas, H.T. Kaptanoǧlu, L. Aizenberg, L. Aizenberg, L. Aizenberg, L. Aizenberg, L. Aizenberg, L. Branges de, L.K. Hua, M. Tomić, P. Lassère, P.B. Djakov, P.G. Dixon, P.L. Duren, R. Balasubramanian, R. Fournier, R.M. Ali, R.M. Ali, S. Dineen, S. Dineen, S. Ponnusamy, S. Sidon, Sh. Chen, Sh. Chen, T. Liu, V.I. Paulsen, V.I. Paulsen, V.I. Paulsen, Y. Abu-Muhanna, Y. Abu-Muhanna, Y. Abu-Muhanna, Y. Abu-Muhanna, Y. Abu-Muhanna, Z. Abdulhadi, Z. Guadarrama, Z. Mao   +53 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Rotationally Symmetric Harmonic Diffeomorphisms between Surfaces

Abstract and Applied Analysis, 2013
We show the nonexistence of rotationally symmetric harmonic diffeomorphism between the unit disk without the origin and a punctured disc with hyperbolic metric on the target.
Li Chen, Shi-Zhong Du, Xu-Qian Fan
doaj   +1 more source

Approximate Noether Symmetries of the Geodesic Equations for the Charged-Kerr Spacetime and Rescaling of Energy

, 2009
Using approximate symmetry methods for differential equations we have investigated the exact and approximate symmetries of a Lagrangian for the geodesic equations in the Kerr spacetime.
Hussain, Ibrar, Mahomed, F. M., Qadir, Asghar   +2 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Mathisson-Papapetrou-Tulczyjew-Dixon (MPTD) equations in ultra-relativistic regime and gravimagnetic moment

, 2016
Mathisson-Papapetrou-Tulczyjew-Dixon (MPTD) equations in the Lagrangian formulation correspond to the minimal interaction of spin with gravity. Due to the interaction, in the Lagrangian equations instead of the original metric $g$ emerges spin-dependent ...
Deriglazov, Alexei A., Ramírez, Walberto Guzmán   +1 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Schwarz-Pick Estimates for Holomorphic Mappings with Values in Homogeneous Ball

Abstract and Applied Analysis, 2012
Let BX be the unit ball in a complex Banach space X. Assume BX is homogeneous. The generalization of the Schwarz-Pick estimates of partial derivatives of arbitrary order is established for holomorphic mappings from the unit ball Bn to BX associated with ...
Jianfei Wang
doaj   +1 more source