Results 51 to 60 of about 158,066 (263)

Almost Ricci–Yamabe soliton on contact metric manifolds [PDF]

open access: yesArab Journal of Mathematical Sciences
Purpose – This paper aims to study almost Ricci–Yamabe soliton in the context of certain contact metric manifolds. Design/methodology/approach – The paper is designed as follows: In Section 3, a complete contact metric manifold with the Reeb vector field
Mohan Khatri, Jay Prakash Singh
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Metric Space with LCOE Isolines for Research Guidance in wind and hydrokinetic energy systems

open access: yesWind Energy, 2020
This paper introduces a new Metric Space to guide the design of advanced wind energy systems and hydrokinetic energy converters such as tidal, ocean current and riverine turbines.
Mario Garcia‐Sanz
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Antimicrobial Use Over a Four-Year Period Using Days of Therapy Measurement at a Canadian Pediatric Acute Care Hospital

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2015
BACKGROUND: Antimicrobial resistance is a concern that is challenging the ability to treat common infections. Surveillance of antimicrobial use in pediatric acute care institutions is complicated because the common metric unit, the defined daily dose, is
Bruce R Dalton   +6 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Some Properties of C ∗ -Graded Metric Spaces and Fixed Point Results

open access: yesJournal of Mathematical Extension, 2010
In this paper, by using of C ∗ -algebra we give a metric with range in positive unit ball of a C ∗ -algebra. Indeed this is a generalization of a fuzzy metric space.
Sh. Sedghi∗, A. Gilani, M. Foozooni
doaj  

On Funk's parabolas

open access: yesREMAT
This study aims to analyze parabolas in the two dimensional unit disk equipped with a Funk metric. The analysis leads to four types of parabolas are obtained, due to the non-reversibility of the Funk metric.
Newton Mayer Solórzano Chávez   +2 more
doaj   +1 more source

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