Results 71 to 80 of about 1,013,760 (323)
Canadian Journal of Infectious Diseases and Medical Microbiology, 2015 BACKGROUND: Antimicrobial resistance is a concern that is challenging the ability to treat common infections. Surveillance of antimicrobial use in pediatric acute care institutions is complicated because the common metric unit, the defined daily dose, is
Bruce R Dalton +6 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
REMATThis study aims to analyze parabolas in the two dimensional unit disk equipped with a Funk metric. The analysis leads to four types of parabolas are obtained, due to the non-reversibility of the Funk metric.
Newton Mayer Solórzano Chávez +2 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Some Properties of C ∗ -Graded Metric Spaces and Fixed Point Results
Journal of Mathematical Extension, 2010 In this paper, by using of C ∗ -algebra we give a metric with range in positive unit ball of a C ∗ -algebra. Indeed this is a generalization of a fuzzy metric space.
Sh. Sedghi∗, A. Gilani, M. Foozooni
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
NASA metric system study [PDF]
Statistical analysis of metric and English unit usage and trends in technical documents generated by NASA ...
Carlson, O., Eckert, P. F.
core +1 more source
Multispectral lighting simulation approaches for predicting opsin-driven metrics and their application in a neonatal intensive care unit [PDF]
, 2023 B. Jung +3 more
openalex +1 more source