Results 101 to 110 of about 2,387,931 (338)

Examining malaria treatment and prevention spending efficiency in malaria-endemic countries, 2000–2020

Malaria Journal
Background In 2021, an estimated 750,000 people died from malaria. Despite this significant burden, globally, malaria incidence and mortality rates have substantially dropped over the last 30 years.
Angela E. Apeagyei, Ian Cogswell, Nishali K. Patel, Kevin O’Rourke, Golsum Tsakalos, Joseph L. Dieleman   +5 more
doaj   +1 more source

Cosmic stringlike objects in hybrid metric-Palatini gravity [PDF]

, 2020
Tiberiu Harko, Francisco S. N. Lobo, Hilberto M. R. da Silva   +2 more
openalex   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Socio-demographic factors of happiness among young adults in Iran

Scientific Reports
This study aimed to measure the socio-demographic factors of happiness among young adults in Iran. A national cross-sectional study measures socio-demographic factors of happiness among a representative sample of young adults (20–39 years).
Ali Montazeri, Samira Mohammadi, Mahmoud Tavousi, Aliasghar Haeri-Mehrizi, Jila Sadighi, Faranak Farzadi, Farzaneh Maftoon, Afsoon Aeenparast, Ramin Mozaffari Kermani   +8 more
doaj   +1 more source

Road-Based Multi-Metric Forwarder Evaluation for Multipath Video Streaming in Urban Vehicular Communication [PDF]

, 2020
Ahmed Aliyu, Abdul Hanan Abdullah, Ismail Fauzi Isnin, Raja Kamil, Arvind Kumar, Tasneem Darwish, Mohammed Joda Usman   +6 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Project Management Metrics [PDF]

Metrics and indicators used for the evaluation of the IT projects management have the advantage of providing rigorous details about the required effort and the boundaries of the IT deliverables.
Radu MARSANU
core