Results 131 to 140 of about 2,387,931 (338)

Delays in Blood Work and Disease Burden: A Cross-Sectional Analysis of Unmet Blood Work Need and Seven Key Health Conditions Across 21 Countries

International Journal of Public Health
ObjectivesThis study analyzes survey data across 21 countries to explore correlations between delays in blood testing and the prevalence of seven health conditions: thalassaemias, sickle cell disorders, malaria, HIV, high fasting plasma glucose, impaired
Eunice Chung, Louisa Ewald, Nicholas J. Kassembaum, Nicholas J. Kassembaum, Taylor Noyes, Emmanuela Gakidou, Emmanuela Gakidou, Ali H. Mokdad, Ali H. Mokdad   +8 more
doaj   +1 more source

Ptolemy’s inequality, chordal metric, multiplicative metric [PDF]

Pacific Journal of Mathematics, 1982
Klamkin, M. S., Meir, A.
openaire   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Differences across the lifespan between females and males in the top 20 causes of disease burden globally: a systematic analysis of the Global Burden of Disease Study 2021

The Lancet Public Health
Summary: Background: Sex and gender shape health. There is a growing body of evidence focused on comprehensively and systematically examining the magnitude, persistence, and nature of differences in health between females and males.
Vedavati Patwardhan, PhD, Gabriela F Gil, MPH, Alejandra Arrieta, MIDP, Jack Cagney, MSc, Erin DeGraw, MPH, Molly E Herbert, MSc, Mariam Khalil, MSc, Erin C Mullany, BA, Erin M O’Connell, BA, Cory N Spencer, MPH, Caroline Stein, PhD, Aiganym Valikhanova, PhD, Emmanuela Gakidou, ProfPhD, Luisa S Flor, PhD   +13 more
doaj   +1 more source

*metrics

, 2020
Lemke, Steffen, Zagovora, Olga, Weller, Katrin, Orth, Astrid, Beucke, Daniel, Stropel, Julius, Peters, Isabell   +6 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Health literacy and mental health: a national cross-sectional inquiry

Scientific Reports
Health literacy and mental health are among the most important issues in the modern health and era of public health. This study aimed to investigate the association between health literacy and mental health status.
Aliasghar Haeri-Mehrizi, Samira Mohammadi, Shahram Rafifar, Jila Sadighi, Ramin Mozaffari Kermani, Rahele Rostami, Akram Hashemi, Mahmoud Tavousi, Ali Montazeri   +8 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Simulated data for census-scale entity resolution research without privacy restrictions: a large-scale dataset generated by individual-based modeling [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research
Background Entity resolution (ER) is the process of identifying and linking records that refer to the same real-world entity. ER is a fundamental challenge in data science, and a common barrier to ER research and development is that the data fields used ...
Abraham Flaxman, Rajan Mudambi, Beatrix Haddock, Nathaniel Blair-Stahn, Alix Pletcher, Matt Kappel, Os Keyes, Syl Lutze, Steve Bachmeier, Alison Bowman, James Albright, Zeb Burke-Conte, Caroline Kinuthia   +12 more
doaj   +1 more source