Results 51 to 60 of about 149,141 (380)

Risk Factors for Treatment Failure and Recurrence after Metronidazole Treatment for Clostridium difficile-associated Diarrhea

Gut and Liver, 2010
Background/Aims: The incidence of treatment failure or recurrence of Clostridium difficile-associated diarrhea (CDAD) following metronidazole treatment has increased recently. We studied the treatment failure, recurrence rate, and risk factors predictive
doaj   +1 more source

METRONIDAZOLE GEL EFFECT ON RATS WITH BACTERIA-INDUCED PERIODONTITIS

ODONTO: Dental Journal, 2020
Background: Periodontitis is an inflammatory disease in the periodontal tissue and causes progressive tissue damage. Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) is directly responsible for the pathogenesis of periodontal diseases.
Muhamat Muhtar S. Abdurrohman, R. Rama Putranto   +1 more
doaj   +1 more source

Circulation of Highly Drug-Resistant Clostridium difficile Ribotypes 027 and 001 in Two Tertiary-Care Hospitals in Mexico [PDF]

, 2018
© 2018, Mary Ann Liebert, Inc.OBJECTIVE: To assess drug susceptibility and characterize Clostridium difficile ribotypes in isolates from two tertiary-care hospitals in Mexico.
Adrian Martinez-Melendez, Adrian, Baines, Simon, Camacho-Ortiz, Adrian, Flores-Trevino, Samantha, Garza-Gonzalez, Elvira, Maldonado-Garza, Hector Jesus, Morfin-Otero, Rayo, Rodrıguez-Noriega, Eduardo, Sanchez-Alanıs, Hugo, Tijerina-Rodrıguez, Laura, Villarreal-Trevino, Licet   +10 more
core   +2 more sources

Comparative Effectiveness of Vancomycin and Metronidazole for the Prevention of Recurrence and Death in Patients With Clostridium difficile Infection

JAMA Internal Medicine, 2017
Importance Metronidazole hydrochloride has historically been considered first-line therapy for patients with mild to moderate Clostridium difficile infection (CDI) but is inferior to vancomycin hydrochloride for clinical cure.
V. Stevens, R. Nelson, Elyse Schwab-Daugherty, K. Khader, Makoto M. Jones, K. Brown, T. Greene, L. D. Croft, M. Neuhauser, P. Glassman, M. Goetz, M. Samore, M. Rubin   +12 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Bioadhesive Controlled Metronidazole Release Matrix Based on Chitosan and Xanthan Gum

Marine Drugs, 2010
Metronidazole, a common antibacterial drug, was incorporated into a hydrophilic polymer matrix composed of chitosan xanthan gum mixture. Hydrogel formation of this binary chitosan-xanthan gum combination was tested for its ability to control the release ...
Ala’a F. Eftaiha, Nidal Qinna, Iyad S. Rashid, Mayyas M. Al Remawi, Munther R. Al Shami, Tawfiq A. Arafat, Adnan A. Badwan   +6 more
doaj   +1 more source

Antibiotic prescribing by general dental practitioners in the Greater Glasgow Health Board, Scotland [PDF]

, 2000
OBJECTIVE: To investigate antibiotic prescribing patterns by general dental practitioners (GDPs) in the Greater Glasgow Health Board Area, Scotland. STUDY DESIGN: A 10% sample of prescriptions were selected at random from 35,545 prescriptions written by ...
Bagg, J., Roy, K.
core   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Sonicated Carbon Nanotube Catalysts for Efficient Point‐of‐use Water Treatment

Advanced Materials, EarlyView.
The growing demand for freshwater and rising contamination of water sources require innovative treatment technologies. Sonicated carbon nanotubes can activate persulfate for selective contaminant degradation via nonradical pathways. This scalable approach enables rapid pollutant removal, offering a sustainable solution for decentralized freshwater ...
Xin Yang, Justin Prabowo, Jiaxiang Chen, Fangxin She, Leo Lai, Fangzhou Liu, Zhechao Hua, Yangyang Wang, Jingyun Fang, Kunli Goh, Di Zhang, Hao Li, Li Wei, Yuan Chen   +13 more
wiley   +1 more source

Role of the rdxA and frxA genes in oxygen-dependent metronidazole resistance of Helicobacter pylori [PDF]

, 2004
Almost 50 % of all Helicobacter pylori isolates are resistant to metronidazole, which reduces the efficacy of metronidazole-containing regimens, but does not make them completely ineffective.
Bax, D.A. (Dorine), Gerrits, M.M. (Monique), Jong, A. (Albertine) de, Kuipers, E.J. (Ernst), Kusters, J.G. (Johannes), Thijs, J.C., Vliet, A.H.M. (Arnoud) van, Wouden, E.J. van der, Zwet, A.A. (Anton) van   +8 more
core   +1 more source